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Tnfsfm13 Gene Detail
Summary
  • Symbol
    Tnfsfm13
  • Name
    tumor necrosis factor (ligand) superfamily, membrane-bound member 13
  • Synonyms
    BC096441, Tnfsf12tnfsf13, Tnfsf12-Tnfsf13, TWE-PRIL
  • Feature Type
    protein coding gene
  • IDs
    MGI:3845075
    NCBI Gene: 619441
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69573403-69586924 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.86 cM
Strain
Comparison
more
  • SNPs within 2kb
    95 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3845075
 protein coding gene Chr11:69573403-69586924 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018548
 protein coding gene Chr11:70141589-70155346 (-)
A/J MGP_AJ_G0018516
 protein coding gene Chr11:67499526-67513016 (-)
AKR/J MGP_AKRJ_G0018485
 protein coding gene Chr11:69509270-69524609 (-)
BALB/cJ MGP_BALBcJ_G0018488
 protein coding gene Chr11:67808952-67822848 (-)
C3H/HeJ MGP_C3HHeJ_G0018301
 protein coding gene Chr11:69541055-69556536 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018939
 protein coding gene Chr11:72262643-72279055 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016584
 protein coding gene Chr11:64418364-64431399 (-)
CAST/EiJ MGP_CASTEiJ_G0017856
 protein coding gene Chr11:69782356-69797594 (-)
CBA/J MGP_CBAJ_G0018274
 protein coding gene Chr11:75499001-75513755 (-)
DBA/2J MGP_DBA2J_G0018383
 protein coding gene Chr11:67081993-67097287 (-)
FVB/NJ MGP_FVBNJ_G0018373
 protein coding gene Chr11:66725299-66739674 (-)
LP/J MGP_LPJ_G0018453
 protein coding gene Chr11:70710152-70723591 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018396
 protein coding gene Chr11:76089545-76110871 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018981
 protein coding gene Chr11:69770896-69785802 (-)
PWK/PhJ MGP_PWKPhJ_G0017630
 protein coding gene Chr11:67731873-67745733 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017420
 protein coding gene Chr11:69590837-69604290 (-)
WSB/EiJ MGP_WSBEiJ_G0017910
 protein coding gene Chr11:69443197-69458404 (-)



Homology
more
  • Human Ortholog
    TNFSF12-TNFSF13, TNFSF12-TNFSF13 readthrough
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TNFSF12-TNFSF13, TNFSF12-TNFSF13 readthrough
  • Synonyms
    TWE-PRIL
  • Links
    NCBI Gene ID: 407977
    neXtProt AC: NX_O43508

  • Chr Location
    17p13.1; chr17:7549058-7561601 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Targeted
    1
  • Genomic Mutations
    2 involving Tnfsfm13
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    4 strains or lines available
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    4
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 619441 NCBI Gene Model | MGI Sequence Detail 13522 C57BL/6J ±  kb
transcript NM_001034097 RefSeq | MGI Sequence Detail 2235 C57BL/6  
polypeptide NP_001029269 RefSeq | MGI Sequence Detail 410 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR021184 Tumour necrosis factor, conserved site
    IPR006052 Tumour necrosis factor domain
    IPR008983 Tumour necrosis factor-like domain superfamily
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:272611 Howard L, et al., TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation. Development. 2018 Nov 19;145(22):dev165936
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory