Il11ra3 Gene Detail

Summary

• Symbol
  Il11ra3
• Name
  interleukin 11 receptor subunit alpha 3
• Synonyms
  Gm13305, Gm2002

• Feature Type
  protein coding gene
• IDs
  MGI:3801997
  NCBI Gene: 100042555
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr4:42158842-42168603 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 22.50 cM
• Mapping Data
  1 experiment

Strain
Comparison

• Strain Annotations
  8

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3801997	protein coding gene	Chr4:42158842-42168603 (-)
129S1/SvImJ	ENSMUSG00200004213	protein coding gene	Chr4:38683001-38692762 (-)
A/J	ENSMUSG00195003192	protein coding gene	Chr4:39162343-39172109 (-)
AKR/J	ENSMUSG00220031839	protein coding gene	Chr4:38916859-38926624 (+)
BALB/cJ	ENSMUSG00180024777	protein coding gene	Chr4:38749159-38758925 (-)
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
JF1/MsJ	no annotation
LP/J	ENSMUSG00230040283	protein coding gene	Chr4:42503800-42513562 (-)
NOD/ShiLtJ	ENSMUSG00190005131	protein coding gene	Chr4:38874582-38884345 (+)
NZO/HlLtJ	ENSMUSG00225006751	protein coding gene	Chr4:46320887-46330653 (-)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  IL11RA, interleukin 11 receptor subunit alpha

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IL11RA, interleukin 11 receptor subunit alpha
  
• Synonyms
  CRSDA
• Links
  HGNC:5967

  NCBI Gene ID: 3590

  UniProt: Q14626

  
  
• Chr Location
  9p13.3; chr9:34651582-34661902 (+)  GRCh38

---

• MGI Vertebrate Homology
  Il11ra3 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: IL11RA
• Gene Tree
  Il11ra3
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  4
• Chemically and radiation induced
  1
• Targeted
  3
• Genomic Mutations
  1 involving Il11ra3
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597
• cDNA Data
  2

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  7
• UniProt
  1
• CCDS
  CCDS51150.1

• Ensembl
  ENSMUSG00000073876 (Evidence)
• NCBI Gene
  100042555

Representative Sequences			Length	Strain/Species
genomic	100042555	NCBI Gene Model | MGI Sequence Detail	9762	C57BL/6J
transcript	NM_001099348	RefSeq | MGI Sequence Detail	1953	Not Specified
polypeptide	P70225	UniProt | EBI | MGI Sequence Detail	432	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR003961 Fibronectin type III
  IPR036116 Fibronectin type III superfamily
  IPR003599 Immunoglobulin domain subtype
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR053073 Interleukin-11/Interleukin-27 subunit beta
  IPR003530 Long hematopoietin receptor, soluble alpha chain, conserved site

Molecular
Reagents

• All nucleic 2

  cDNA 2

  
  

  Microarray probesets 2

Other
Accession IDs

MGI:3780172, MGI:7525398

References

• Summaries
  All 14

  Phenotypes 2
• Earliest
  J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
• Latest
  J:389486 Mouse Genome Informatics and Ensembl Genome Database Project, MGI Strain Genome Feature and Gene Model Load from Ensembl. Database Release. 2026;