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Trp53cor1 Gene Detail
Summary
  • Symbol
    Trp53cor1
  • Name
    tumor protein p53 pathway corepressor 1
  • Synonyms
    Gm16197, lincRNA-p21
  • Feature Type
    lncRNA gene
  • IDs
    MGI:3801771
    NCBI Gene: 100504267
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:29276448-29298100 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 15.04 cM
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3801771
lncRNA gene Chr17:29276404-29298153 (-)
129S1/SvImJ MGP_129S1SvImJ_G0005713
lincRNA gene Chr17:28558122-28581035 (-)
A/J MGP_AJ_G0005702
lincRNA gene Chr17:27571327-27595113 (-)
AKR/J MGP_AKRJ_G0005681
lincRNA gene Chr17:27806130-27829055 (-)
BALB/cJ MGP_BALBcJ_G0005682
lincRNA gene Chr17:27857718-27879002 (-)
C3H/HeJ MGP_C3HHeJ_G0005629
lincRNA gene Chr17:28190397-28215414 (-)
C57BL/6NJ MGP_C57BL6NJ_G0005840
lincRNA gene Chr17:29693618-29717427 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0005193
lincRNA gene Chr17:24914451-24936190 (-)
CAST/EiJ MGP_CASTEiJ_G0005571
lincRNA gene Chr17:28172027-28195572 (-)
CBA/J MGP_CBAJ_G0005617
lincRNA gene Chr17:30789771-30818261 (-)
DBA/2J MGP_DBA2J_G0005635
lincRNA gene Chr17:27116805-27138211 (-)
FVB/NJ MGP_FVBNJ_G0005661
lincRNA gene Chr17:26943438-26965168 (-)
LP/J MGP_LPJ_G0005716
lincRNA gene Chr17:28812489-28835633 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0005646
lincRNA gene Chr17:30151688-30175775 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0005840
lincRNA gene Chr17:28260166-28281500 (-)
PWK/PhJ MGP_PWKPhJ_G0005517
lincRNA gene Chr17:25950090-25975659 (-)
SPRET/EiJ MGP_SPRETEiJ_G0005436
lincRNA gene Chr17:26258560-26281659 (-)
WSB/EiJ MGP_WSBEiJ_G0005623
lincRNA gene Chr17:28228553-28249838 (-)



Homology
more
  • Human Ortholog
    TP53COR1, tumor protein p53 pathway corepressor 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TP53COR1, tumor protein p53 pathway corepressor 1
  • Synonyms
    linc-p21, lincRNA-p21, TRP53COR1
  • Links
    NCBI Gene ID: 102800311

  • Chr Location
    6p21.2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display limb grasping.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 100504267 NCBI Gene Model | MGI Sequence Detail 21653 C57BL/6J ±  kb
transcript NR_036469 RefSeq | MGI Sequence Detail 3121 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:325059 Winkler L, et al., Functional elements of the cis-regulatory lincRNA-p21. Cell Rep. 2022 Apr 19;39(3):110687

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory