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Del(16Dgcr2-Hira)3Aam Complex/Cluster/Region Detail
Summary
  • Symbol
    Del(16Dgcr2-Hira)3Aam
  • Name
    deletion, Chr 16, Alea A Mills 3
  • Synonyms
    Del(16)2Aam, Del2Aam, Df(16)A
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:3798957
Location & Maps
more
  • Genetic Map
    Chromosome 16, Syntenic
Human Diseases
more
  • Diseases
    2 with Del(16Dgcr2-Hira)3Aam mouse models

Human Disease Mouse Models
       DiGeorge Syndrome; DGS   OMIM: 188400 View 1 model
Schizophrenia; SCZD   OMIM: 181500 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 3 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Targeted
    1
Polymorphisms
less
  • SNPs within 2kb
    1759 from dbSNP Build 142
References
more
  • Summaries
    All 13
    Diseases 6
    Phenotypes 12
  • Earliest
    J:136969 Stark KL, et al., Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet. 2008 Jun;40(6):751-60
  • Latest
    J:235604 Nilsson SR, et al., Assessing the Cognitive Translational Potential of a Mouse Model of the 22q11.2 Microdeletion Syndrome. Cereb Cortex. 2016 Oct;26(10):3991-4003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory