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Ugt1 Complex/Cluster/Region Detail
Summary
  • Symbol
    Ugt1
  • Name
    UDP glucuronosyltransferase 1 complex
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:3785283
  • Cluster Members
    Ugt1a10, Ugt1a9, Ugt1a8 ... (10 members)
Location & Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 1, Syntenic
Human Diseases
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  • Diseases
    1 with Ugt1 mouse models

Human Disease Mouse Models
      
IDs
View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    20 phenotypes from 2 alleles in 2 genetic backgrounds
    1 images
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a mutation disrupting the entire complex display postnatal lethality with jaundice and very high serum levels of unconjugated bilirubin.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2
    References
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    • Summaries
      All 16
      Developmental Gene Expression 3
      Diseases 2
      Phenotypes 12
    • Earliest
      J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
    • Latest
      J:262285 Porro F, et al., Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model. EMBO Mol Med. 2017 Oct;9(10):1346-1355

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    07/10/2018
    MGI 6.12
    The Jackson Laboratory