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Ugt1
Complex/Cluster/Region Detail
 Symbol
Name
ID
Cluster members
Ugt1
UDP glucuronosyltransferase 1 complex
MGI:3785283
Ugt1a10, Ugt1a9, Ugt1a8 ... (10 members)
Feature Type complex/cluster/region
Genetic Map
Chromosome 1
Syntenic
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
 
Mice homozygous for a mutation disrupting the entire complex display postnatal lethality with jaundice and very high serum levels of unconjugated bilirubin.
 
Human Diseases Modeled Using Mouse Ugt1 (1)    Alleles Annotated to Human Diseases(2)    Phenotype Images(1)
Expression
Literature Summary: (3 records)
Data Summary: Results (164)    Tissues (140)    Images (20)
Theiler Stages: 22, 23, 26, 28
Assay TypeResults
RNA in situ 164
cDNA source data(2)
Molecular
reagents
All nucleic(2) cDNA(2)
References (Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:209506 Yueh MF, et al., Developmental onset of bilirubin-induced neurotoxicity involves Toll-like receptor 2-dependent signaling in humanized UDP-glucuronosyltransferase1 mice. J Biol Chem. 2014 Feb 21;289(8):4699-709
All references(10)
Disease annotation references (2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory