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Ugt1 Complex/Cluster/Region Detail
Summary
  • Symbol
    Ugt1
  • Name
    UDP glucuronosyltransferase 1 complex
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:3785283
  • Cluster Members
    Ugt1a10, Ugt1a9, Ugt1a8 ... (10 members)
Location & Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 1, Syntenic
Human Diseases
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  • Diseases
    1 with Ugt1 mouse models

Human Disease Mouse Models
       Crigler-Najjar Syndrome, Type I   OMIM: 218800 View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    20 phenotypes from 2 alleles in 2 genetic backgrounds
    1 images
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    2
  • Targeted
    2
Mice homozygous for a mutation disrupting the entire complex display postnatal lethality with jaundice and very high serum levels of unconjugated bilirubin.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Molecular
Reagents
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  • All nucleic 2
    cDNA 2
References
more
  • Summaries
    All 12
    Developmental Gene Expression 3
    Diseases 2
    Phenotypes 7
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:226092 Fujiwara R, et al., Role of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding breast milk-induced neonatal hyperbilirubinemia. Toxicol Appl Pharmacol. 2015 Nov 15;289(1):124-32

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory