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Sirpb1b Gene Detail
Summary
  • Symbol
    Sirpb1b
  • Name
    signal-regulatory protein beta 1B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3779828
    NCBI Gene: 668101
  • Gene Overview
    MyGene.info: SIRPB1
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:15495754-15575067 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 3.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    660 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3779828
protein coding gene Chr3:15495751-15575067 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027081
protein coding gene Chr3:12527196-13050306 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0027056
protein coding gene Chr3:12675684-12732110 (-)
C3H/HeJ MGP_C3HHeJ_G0026795
protein coding gene Chr3:13023997-13061137 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027500
protein coding gene Chr3:13476728-13570888 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024862
protein coding gene Chr3:11056015-11090238 (-)
CAST/EiJ MGP_CASTEiJ_G0026252
protein coding gene Chr3:12834681-12845133 (-)
CBA/J MGP_CBAJ_G0026773
protein coding gene Chr3:13751523-13850785 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0026875
protein coding gene Chr3:11856700-12311343 (-)
LP/J MGP_LPJ_G0027019
protein coding gene Chr3:13309898-13355176 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025792
protein coding gene Chr3:12383768-12606780 (-)
WSB/EiJ MGP_WSBEiJ_G0026323
protein coding gene Chr3:12521120-12560138 (-)



Homology
more
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Vertebrate Orthologs
    14
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
    Orthology source: HomoloGene
  • Synonyms
    CD172b, SIRP-BETA-1
  • Links
    NCBI Gene ID: 10326
    neXtProt AC: NX_O00241, NX_Q5TFQ8
    UniProt: O00241, Q5TFQ8

  • Chr Location
    20p13; chr20:1564193-1620457 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 668101 NCBI Gene Model | MGI Sequence Detail 79314 C57BL/6J ±  kb
transcript NM_001173460 RefSeq | MGI Sequence Detail 1496 C57BL/6  
polypeptide NP_001166931 RefSeq | MGI Sequence Detail 391 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 15
    Diseases 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory