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C1rb Gene Detail
Summary
  • Symbol
    C1rb
  • Name
    complement component 1, r subcomponent B
  • Synonyms
    Gm8551, mC1rB
  • Feature Type
    protein coding gene
  • IDs
    MGI:3779804
    NCBI Gene: 667277
  • Gene Overview
    MyGene.info: C1R
Location & Maps
more
  • Sequence Map
    Chr6:124570294-124581171 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10878 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    C1R, complement C1r
  • Vertebrate Orthologs
    9
  • Human Ortholog
    C1R, complement C1r
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 715
    neXtProt AC: NX_P00736

  • Chr Location
    12p13

Human Diseases
more
  • Diseases
    1 with human C1R associations

Human Disease Mouse Models
       Complement Component C1r/C1s Deficiency   OMIM: 216950
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044915 VEGA Gene Model | MGI Sequence Detail 10878 C57BL/6J ±  kb
transcript OTTMUST00000118064 VEGA | MGI Sequence Detail 2429 Not Applicable  
polypeptide OTTMUSP00000065944 VEGA | MGI Sequence Detail 706 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    46 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 14
    Gene Ontology 3
  • Earliest
    J:121092 Byun SJ, et al., IFN-gamma upregulates expression of the mouse complement C1rA gene in keratinocytes via IFN-regulatory factor-1. J Invest Dermatol. 2007 May;127(5):1187-96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory