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C1rb Gene Detail
Summary
  • Symbol
    C1rb
  • Name
    complement component 1, r subcomponent B
  • Synonyms
    Gm8551, mC1rB
  • Feature Type
    protein coding gene
  • IDs
    MGI:3779804
    NCBI Gene: 667277
  • Gene Overview
    MyGene.info: C1R
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124570430-124581044 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3779804
protein coding gene Chr6:124570294-124581171 (.)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0031154
protein coding gene Chr6:126295762-126306157 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0030917
protein coding gene Chr6:136259296-136272532 (+)
DBA/2J MGP_DBA2J_G0031073
protein coding gene Chr6:121912089-121972991 (+)
FVB/NJ MGP_FVBNJ_G0031024
protein coding gene Chr6:120868624-120890591 (+)
LP/J MGP_LPJ_G0031154
protein coding gene Chr6:127979473-127996420 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031061
protein coding gene Chr6:140223897-140234575 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031724
protein coding gene Chr6:126208074-126223888 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0030422
protein coding gene Chr6:126621794-126661755 (+)



Homology
more
  • Human Ortholog
    C1R, complement C1r
  • Vertebrate Orthologs
    9
  • Human Ortholog
    C1R, complement C1r
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EDSPD1
  • Links
    NCBI Gene ID: 715
    neXtProt AC: NX_P00736
    UniProt: P00736

  • Chr Location
    12p13.31; chr12:7080209-7092447 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 667277 NCBI Gene Model | MGI Sequence Detail 10615 C57BL/6J ±  kb
transcript NM_001113356 RefSeq | MGI Sequence Detail 2166 C57BL/6  
polypeptide Q8CFG9 UniProt | EBI | MGI Sequence Detail 706 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 16
    Gene Ontology 5
  • Earliest
    J:83033 Garnier G, et al., Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system. Biochem J. 2003 Apr 15;371(Pt 2):631-40
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory