Nat8f6 Gene Detail

Summary

• Symbol
  Nat8f6
• Name
  N-acetyltransferase 8 (GCN5-related) family member 6
• Synonyms
  Gm11128

• Feature Type
  protein coding gene
• IDs
  MGI:3779382
  NCBI Gene: 100504710
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr6:85785026-85786859 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 37.48 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  101 from dbSNP Build 142
• Strain Annotations
  16

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3779382	protein coding gene	Chr6:85785006-85797936 (-)
129S1/SvImJ	ENSMUSG00200041289	protein coding gene	Chr6:82693999-82699084 (-)
A/J	ENSMUSG00195037809	protein coding gene	Chr6:82378318-82383395 (-)
AKR/J	ENSMUSG00220027278	protein coding gene	Chr6:81336393-81349325 (-)
AKR/J	ENSMUSG00220001828	protein coding gene	Chr6:81289610-81294695 (-)
BALB/cJ	ENSMUSG00180014851	protein coding gene	Chr6:82811033-82823963 (-)
C3H/HeJ	ENSMUSG00175037503	protein coding gene	Chr6:94645942-94651023 (+)
C57BL/6NJ	ENSMUSG00215019771	protein coding gene	Chr6:82806633-82819563 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028584	protein coding gene	Chr6:81842778-81844163 (-)
CAST/EiJ	ENSTCUG00005017247	protein coding gene	Chr6:82749863-82751898 (-)
CBA/J	ENSMUSG00210034743	protein coding gene	Chr6:82569488-82574569 (-)
DBA/2J	ENSMUSG00185042904	protein coding gene	Chr6:83116634-83121715 (-)
FVB/NJ	no annotation
JF1/MsJ	no annotation
LP/J	ENSMUSG00230044148	protein coding gene	Chr6:84250650-84255735 (-)
NOD/ShiLtJ	ENSMUSG00190041845	protein coding gene	Chr6:82193265-82198346 (-)
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	ENSMSPG00010031438	protein coding gene	Chr6:83677931-83679947 (-)
WSB/EiJ	ENSIUOG00005030824	protein coding gene	Chr6:83146097-83148131 (-)

Homology

• Human Ortholog
  NAT8, N-acetyltransferase 8 (putative)

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  NAT8, N-acetyltransferase 8 (putative)
  
• Synonyms
  ATase2, CCNAT, CML1, GLA, Hcml1, TSC501, TSC510
• Links
  HGNC:18069

  NCBI Gene ID: 9027

  UniProt: Q9UHE5

  
  
• Chr Location
  2p13.1; chr2:73640723-73643229 (-)  GRCh38

---

• Human Ortholog
  NAT8B, N-acetyltransferase 8B (putative, gene/pseudogene)
  
• Synonyms
  CML2, Hcml2, NAT8BP
• Links
  HGNC:30235

  NCBI Gene ID: 51471

  UniProt: Q9UHF3

  
  
• Chr Location
  2p13.1; chr2:73700509-73702125 (-)  GRCh38

---

• MGI Vertebrate Homology
  Nat8f6 stringent orthology
  2 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: NAT8, NAT8B
• Gene Tree
  Nat8f6
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  1
• Spontaneous
  1
• Genomic Mutations
  1 involving Nat8f6
• Find Mice (IMSR)
  8 strains or lines available

Expression

• Assay Results
  597
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  26
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS51830.1

• Ensembl
  ENSMUSG00000079495 (Evidence)
• NCBI Gene
  100504710

Representative Sequences			Length	Strain/Species
genomic	100504710	NCBI Gene Model | MGI Sequence Detail	1834	C57BL/6J
transcript	NM_001201389	RefSeq | MGI Sequence Detail	1395	ZRU/MplStud
polypeptide	Q9JIY8	UniProt | EBI | MGI Sequence Detail	226	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 1

  cDNA 1

References

• Summaries
  All 17

  Phenotypes 7
• Earliest
  J:69958 Popsueva AE, et al., Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis. Dev Biol. 2001 Jun 15;234(2):483-96
• Latest
  J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376