Nlgn4l
Gene Detail

Symbol Name ID

Nlgn4l neuroligin 4-like MGI:3775191

Synonyms

NL4, NL-4, Nlgn4

Feature Type

protein coding gene

Genetic Map

Chromosome Unknown

Alleles and phenotypes

All alleles(1) : Gene trapped(1)
 

Homozygous mutation of this gene results in deficits in reciprocal social interaction and communication as well as small reduction of total brain and brain stem volume.

 
Human Diseases Modeled Using Mouse Nlgn4l (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(1)

Gene Ontology (GO) classifications

All GO classifications: (19 annotations)

Process	brainstem development, cerebellum development, ...
Component	cell junction, cell surface, ...
Function	neurexin family protein binding, receptor activity

Expression

Literature Summary: (1 records)

Other database links

Entrez Gene	100113365
UniGene	468446

Sequences

Length	Strain/Species
transcript	EF692521	GenBank | EMBL | DDBJ | MGI Sequence Detail	3402	BALB/c
polypeptide	B0F2B4	UniProt | EBI | MGI Sequence Detail	945	Not Applicable

All sequences(3) UniProt(1)

Protein-related information

Resource	ID	Description
InterPro	IPR002018	Carboxylesterase, type B
InterPro	IPR019819	Carboxylesterase type B, conserved site
Protein Ontology	PR:000033559	neuroligin 4-like

Graphical View of Protein Domain Structure

References

(Earliest) J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
(Latest) J:192982 Poulopoulos A, et al., Homodimerization and isoform-specific heterodimerization of neuroligins. Biochem J. 2012 Sep 1;446(2):321-30
All references(12)