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Nlgn4l
Gene Detail
Symbol

Name
ID
Nlgn4l
neuroligin 4-like
MGI:3775191
Synonyms
NL4, NL-4, Nlgn4
Feature Type
protein coding gene
Genetic Map
Chromosome Unknown
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
 
Homozygous mutation of this gene results in deficits in reciprocal social interaction and communication as well as small reduction of total brain and brain stem volume.
 
Human Diseases Modeled Using Mouse Nlgn4l (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(1)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process brainstem development, cerebellum development, ...
Component cell junction, integral component of membrane, ...
Expression
Literature Summary: (1 records)
Other database
links
Entrez Gene100113365
UniGene468446
Sequences
Representative SequencesLengthStrain/SpeciesFlank
transcript EF692521 GenBank | EMBL | DDBJ | MGI Sequence Detail 3402 BALB/c 
polypeptide B0F2B4 UniProt | EBI | MGI Sequence Detail 945 Not Applicable 

For the selected sequences
All sequences(3) UniProt(1)
Protein-related
information
ResourceIDDescription
InterPro IPR002018 Carboxylesterase, type B
InterPro IPR019819 Carboxylesterase type B, conserved site
Protein Ontology PR:000033559 neuroligin 4-like
Graphical View of Protein Domain Structure
References
(Earliest) J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
(Latest) J:207789 Delattre V, et al., Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro. Sci Rep. 2013;3:2897
All references(14)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory