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Srp54c Gene Detail
Summary
  • Symbol
    Srp54c
  • Name
    signal recognition particle 54C
  • Synonyms
    E330029E12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3714359
    NCBI Gene: 100101806
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr12:55230168-55263836 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 23.89 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    75 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3714359
protein coding gene Chr12:55230111-55280015 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019744
protein coding gene Chr12:54049837-54076685 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0019676
protein coding gene Chr12:53929851-53973485 (+)
BALB/cJ MGP_BALBcJ_G0019683
protein coding gene Chr12:52430344-52468886 (+)
C3H/HeJ MGP_C3HHeJ_G0019486
protein coding gene Chr12:53827080-53862286 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020135
protein coding gene Chr12:55868831-55906007 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017754
protein coding gene Chr12:50404743-50439276 (+)
CAST/EiJ MGP_CASTEiJ_G0019039
protein coding gene Chr12:48860082-48894903 (+)
CBA/J MGP_CBAJ_G0019458
protein coding gene Chr12:57815431-57862238 (+)
DBA/2J MGP_DBA2J_G0019572
protein coding gene Chr12:51988045-52030562 (+)
FVB/NJ MGP_FVBNJ_G0019561
protein coding gene Chr12:51463929-51494138 (+)
LP/J MGP_LPJ_G0019644
protein coding gene Chr12:54103147-54145861 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019597
protein coding gene Chr12:59226922-59371862 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020169
protein coding gene Chr12:53205382-53239706 (+)
PWK/PhJ MGP_PWKPhJ_G0018806
protein coding gene Chr12:46564954-46599499 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018600
protein coding gene Chr12:47787989-47807633 (+)
WSB/EiJ MGP_WSBEiJ_G0019090
protein coding gene Chr12:53866185-53915948 (+)



Homology
more
  • Human Ortholog
    SRP54, signal recognition particle 54
  • Vertebrate Orthologs
    1
  • Human Ortholog
    SRP54, signal recognition particle 54
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 6729
    neXtProt AC: NX_P61011
    UniProt: P61011

  • Chr Location
    14q13.2; chr14:34982645-35029567 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human SRP54 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Expression
less
  • cDNA Data
  • Other Mouse Links
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079108 Ensembl Gene Model | MGI Sequence Detail 33669 C57BL/6J ±  kb
transcript ENSMUST00000218879 Ensembl | MGI Sequence Detail 3642 Not Applicable  
polypeptide ENSMUSP00000151681 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR028260 FAM177 family
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR013822 Signal recognition particle SRP54, helical bundle
    IPR042101 Signal recognition particle SRP54, N-terminal domain superfamily
    IPR022941 Signal recognition particle, SRP54 subunit
    IPR006325 Signal recognition particle, SRP54 subunit, eukaryotic
    IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain
    IPR004125 Signal recognition particle, SRP54 subunit, M-domain
    IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
Other
Accession IDs
less
MGI:2442031
References
more
  • Summaries
    All 21
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory