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Ly6c2 Gene Detail
Summary
  • Symbol
    Ly6c2
  • Name
    lymphocyte antigen 6 complex, locus C2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3712069
    NCBI Gene: 100041546
  • Member of
    Ly6 cluster
Location & Maps
more
  • Sequence Map
    Chr15:75108158-75111970 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3813 bp   ±  kb flank

  • Genome Browsers
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    3
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Ly6c2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045164 VEGA Gene Model | MGI Sequence Detail 3813 C57BL/6J ±  kb
transcript OTTMUST00000118689 VEGA | MGI Sequence Detail 538 Not Applicable  
polypeptide OTTMUSP00000066241 VEGA | MGI Sequence Detail 131 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    72 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000002980 lymphocyte antigen 6C2
  • InterPro Domains
    IPR018363 CD59 antigen, conserved site
    IPR016054 Ly-6 antigen/uPA receptor-like
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20
References
more
  • Summaries
    All 15
    Diseases 1
    Gene Ontology 1
    Phenotypes 21
  • Earliest
    J:35255 Takikawa O, et al., Multiple expression of Ly-6C and accumulation of a Ly-6C pre-mRNA in activated macrophages involved in rejection of an allografted tumor. Biochem Biophys Res Commun. 1996 Sep 4;226(1):247-53
  • Latest
    J:191745 Ramachandran P, et al., Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):E3186-95

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory