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Cphx1 Gene Detail
Summary
  • Symbol
    Cphx1
  • Name
    cytoplasmic polyadenylated homeobox 1
  • Synonyms
    C330003B14Rik, Cphx, Cphx2, Cphx3, Eso-1, Gm2104, Gm2135
Location &
Maps
more
  • Sequence Map
    Chr14:25941983-25956798 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 15.53 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145733
protein coding gene Chr14:25938728-25956798 (+)
129S1/SvImJ ENSMUSG00200014041
protein coding gene Chr14:17747180-17761105 (+)
A/J ENSMUSG00195019063
protein coding gene Chr14:18815110-18829042 (+)
AKR/J ENSMUSG00220023126
protein coding gene Chr14:17914733-17928659 (+)
BALB/cJ ENSMUSG00180034273
protein coding gene Chr14:17906985-17920912 (+)
C3H/HeJ ENSMUSG00175020508
protein coding gene Chr14:17974587-17988511 (+)
C57BL/6NJ ENSMUSG00215024318
protein coding gene Chr14:18222810-18236800 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005027123
protein coding gene Chr14:18075124-18089112 (+)
CBA/J ENSMUSG00210025481
protein coding gene Chr14:18209365-18223288 (+)
DBA/2J ENSMUSG00185035584
protein coding gene Chr14:22504064-22518052 (+)
FVB/NJ ENSMUSG00205031919
protein coding gene Chr14:18036344-18050274 (+)
JF1/MsJ ENSUMUG00000031942
protein coding gene Chr14:29730959-29744889 (+)
LP/J ENSMUSG00230036118
protein coding gene Chr14:29776174-29790100 (+)
NOD/ShiLtJ ENSMUSG00190029678
protein coding gene Chr14:18220180-18234119 (+)
NZO/HlLtJ ENSMUSG00225035969
protein coding gene Chr14:24106506-24120325 (+)
NZO/HlLtJ ENSMUSG00225036763
protein coding gene Chr14:24009723-24023541 (+)
PWK/PhJ ENSLUMG00010020417
protein coding gene Chr14:6341034-6354961 (+)
SPRET/EiJ ENSMSPG00010029073
protein coding gene Chr14:19874097-19887981 (+)
WSB/EiJ ENSIUOG00005028189
protein coding gene Chr14:18052065-18066056 (+)



Homology
more
  • Human Ortholog
    CPHXL, cytoplasmic polyadenylated homeobox like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPHXL, cytoplasmic polyadenylated homeobox like
  • Synonyms
    CPHXL1
  • Links
    NCBI Gene ID: 105371346
    UniProt: A0A1W2PPM1

  • Chr Location
    chr16:75714131-75726490 (-)  GRCh38

  • Human Ortholog
    CPHXL2, cytoplasmic polyadenylated homeobox like 2
  • Links
    NCBI Gene ID: 112268164
    UniProt: A0A1W2PPK0

  • Chr Location
    chr16:75660227-75677009 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 105594 NCBI Gene Model | MGI Sequence Detail 14816 C57BL/6J ±  kb
transcript NM_175342 RefSeq | MGI Sequence Detail 1653 C57BL/6  
polypeptide NP_780551 RefSeq | MGI Sequence Detail 182 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050720 Engrailed Homeobox Transcription Factors
    IPR001356 Homeodomain
    IPR009057 Homeodomain-like superfamily
Molecular
Reagents
less
  • All nucleic 28
    cDNA 22
    Primer pair 4
    Other 2

    Microarray probesets 9
Other
Accession IDs
less
MGI:2145746, MGI:2145864, MGI:3711264, MGI:3780272
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:267468 Bethune MT, et al., Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10702-E10711

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory