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Amy2a2 Gene Detail
Summary
  • Symbol
    Amy2a2
  • Name
    amylase 2a2
  • Synonyms
    mAmy2-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:3711220
    NCBI Gene: 100043688
  • Member of
    Amy cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:113345055-113356658 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 49.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    6
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3711220
protein coding gene Chr3:113345049-113356658 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0025552
protein coding gene Chr3:107407155-107418916 (-)
CAST/EiJ MGP_CASTEiJ_G0026955
protein coding gene Chr3:113969417-113982549 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0027724
protein coding gene Chr3:116547642-116645726 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0028270
protein coding gene Chr3:113948394-113959224 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0026503
protein coding gene Chr3:111802025-111817997 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    AMY1A, amylase alpha 1A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AMY1A, amylase alpha 1A
    Orthology source: HGNC
  • Synonyms
    AMY1
  • Links
    NCBI Gene ID: 276
    neXtProt AC: NX_P04745
    UniProt: P04745

  • Chr Location
    1p21.1; chr1:103655519-103664551 (+)  GRCh38.p7

  • Human Ortholog
    AMY1B, amylase alpha 1B
    Orthology source: HGNC
  • Synonyms
    AMY1
  • Links
    NCBI Gene ID: 277
    neXtProt AC: NX_P04745
    UniProt: P04745

  • Chr Location
    1p21.1; chr1:103687415-103696452 (-)  GRCh38.p7

  • Human Ortholog
    AMY1C, amylase alpha 1C
    Orthology source: HGNC
  • Synonyms
    AMY1
  • Links
    NCBI Gene ID: 278
    neXtProt AC: NX_P04745
    UniProt: P04745

  • Chr Location
    1p21.1; chr1:103745430-103758692 (+)  GRCh38.p7

  • Human Ortholog
    AMY2A, amylase alpha 2A
    Orthology source: HGNC
  • Synonyms
    AMY2, PA
  • Links
    NCBI Gene ID: 279
    neXtProt AC: NX_P04746
    UniProt: P04746

  • Chr Location
    1p21.1; chr1:103617332-103625780 (+)  GRCh38.p7

  • Human Ortholog
    AMY2B, amylase alpha 2B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AMY2, AMY3, HXA
  • Links
    NCBI Gene ID: 280
    neXtProt AC: NX_P19961
    UniProt: P19961

  • Chr Location
    1p21.1; chr1:103554644-103579534 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Amy2a2
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096569 Ensembl Gene Model | MGI Sequence Detail 11604 C57BL/6J ±  kb
transcript ENSMUST00000098667 Ensembl | MGI Sequence Detail 3717 Not Applicable  
polypeptide ENSMUSP00000096264 Ensembl | MGI Sequence Detail 508 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
References
more
  • Summaries
    All 19
    Diseases 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:6365 Hagenbuchle O, et al., Tissue-specific expression of mouse-alpha-amylase genes: nucleotide sequence of isoenzyme mRNAs from pancreas and salivary gland. Cell. 1980 Aug;21(1):179-87
  • Latest
    J:118234 Sugino H, Comparative genomic analysis of the mouse and rat amylase multigene family. FEBS Lett. 2007 Feb 6;581(3):355-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory