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Mettl7a3 Gene Detail
Summary
  • Symbol
    Mettl7a3
  • Name
    methyltransferase like 7A3
  • Synonyms
    Gm10035
  • Feature Type
    protein coding gene
  • IDs
    MGI:3710670
    NCBI Gene: 668178
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr15:100232810-100238256 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    38 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3710670
protein coding gene Chr15:100232687-100246267 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0022310
protein coding gene Chr15:98160617-98172140 (+)
AKR/J MGP_AKRJ_G0022286
protein coding gene Chr15:101187503-101205875 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0022085
protein coding gene Chr15:101295332-101303389 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022760
protein coding gene Chr15:106053363-106099712 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020288
protein coding gene Chr15:94047063-94053034 (+)
CAST/EiJ MGP_CASTEiJ_G0021610
protein coding gene Chr15:102136962-102146069 (+)
CBA/J MGP_CBAJ_G0022054
protein coding gene Chr15:109766161-109806255 (+)
DBA/2J MGP_DBA2J_G0022180
protein coding gene Chr15:97580198-97594978 (+)
FVB/NJ MGP_FVBNJ_G0022159
protein coding gene Chr15:96573727-96590701 (+)
LP/J MGP_LPJ_G0022252
protein coding gene Chr15:102381033-102389315 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022181
protein coding gene Chr15:113517230-113528007 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022777
protein coding gene Chr15:101285408-101295848 (+)
PWK/PhJ MGP_PWKPhJ_G0021349
protein coding gene Chr15:97770045-97779478 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0021659
protein coding gene Chr15:101819529-101827371 (+)



Homology
more
  • Human Ortholog
    METTL7A, methyltransferase like 7A
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    METTL7A, methyltransferase like 7A
  • Synonyms
    AAMB, AAM-B
  • Links
    NCBI Gene ID: 25840
    neXtProt AC: NX_Q9H8H3
    UniProt: Q9H8H3

  • Chr Location
    12q13.12; chr12:50923811-50932517 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058057 Ensembl Gene Model | MGI Sequence Detail 5447 C57BL/6J ±  kb
transcript ENSMUST00000075420 Ensembl | MGI Sequence Detail 1652 Not Applicable  
polypeptide ENSMUSP00000074875 Ensembl | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 31
    Diseases 1
    Gene Ontology 2
    Phenotypes 20
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/28/2022
MGI 6.20
The Jackson Laboratory