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Myh7b Gene Detail
Summary
  • Symbol
    Myh7b
  • Name
    myosin, heavy chain 7B, cardiac muscle, beta
  • Synonyms
    Myh14
  • Feature Type
    protein coding gene
  • IDs
    MGI:3710243
    NCBI Gene: 668940
  • Gene Overview
    MyGene.info: MYH7B
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:155611243-155634307 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 77.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    227 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3710243
protein coding gene Chr2:155611212-155634307 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026738
protein coding gene Chr2:160447067-160470277 (+)
A/J MGP_AJ_G0026704
protein coding gene Chr2:154067328-154090453 (+)
AKR/J MGP_AKRJ_G0026675
protein coding gene Chr2:158535969-158559055 (+)
BALB/cJ MGP_BALBcJ_G0026713
protein coding gene Chr2:154370257-154393417 (+)
C3H/HeJ MGP_C3HHeJ_G0026456
protein coding gene Chr2:158898682-158921902 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027162
protein coding gene Chr2:165148097-165171179 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024532
protein coding gene Chr2:147566576-147590180 (+)
CAST/EiJ MGP_CASTEiJ_G0025917
protein coding gene Chr2:159211600-159234595 (+)
CBA/J MGP_CBAJ_G0026433
protein coding gene Chr2:171148862-171172001 (+)
DBA/2J MGP_DBA2J_G0026570
protein coding gene Chr2:153248221-153271314 (+)
FVB/NJ MGP_FVBNJ_G0026537
protein coding gene Chr2:151625768-151648995 (+)
LP/J MGP_LPJ_G0026675
protein coding gene Chr2:160589780-160614427 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026558
protein coding gene Chr2:175141222-175165230 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027218
protein coding gene Chr2:158423274-158446438 (+)
PWK/PhJ MGP_PWKPhJ_G0025651
protein coding gene Chr2:152745592-152768699 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025454
protein coding gene Chr2:157349792-157373002 (+)
WSB/EiJ MGP_WSBEiJ_G0025987
protein coding gene Chr2:159310844-159334020 (+)



Homology
more
  • Human Ortholog
    MYH7B, myosin heavy chain 7B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYH7B, myosin heavy chain 7B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MHC14, MYH14
  • Links
    NCBI Gene ID: 57644
    neXtProt AC: NX_A7E2Y1
    UniProt: A7E2Y1

  • Chr Location
    20q11.22; chr20:34955835-35002437 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 668940 NCBI Gene Model | MGI Sequence Detail 23065 C57BL/6J ±  kb
transcript NM_001085378 RefSeq | MGI Sequence Detail 6132 C57BL/6  
polypeptide A2AQP0 UniProt | EBI | MGI Sequence Detail 1941 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 3
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Developmental Gene Expression 6
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:210667 Lewandowski SL, et al., Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis. Hum Mol Genet. 2014 Jul 15;23(14):3801-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory