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Mir181d Gene Detail
Summary
  • Symbol
    Mir181d
  • Name
    microRNA 181d
  • Synonyms
    Mirn181d, mmu-mir-181d
Location &
Maps
more
  • Sequence Map
    Chr8:84905345-84905416 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 40.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    13 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3709847
miRNA gene Chr8:84905345-84905416 (-)
129S1/SvImJ MGP_129S1SvImJ_G0009122
miRNA gene Chr8:85053305-85053376 (-)
A/J MGP_AJ_G0009103
miRNA gene Chr8:81723184-81723255 (-)
AKR/J MGP_AKRJ_G0009094
miRNA gene Chr8:84138215-84138286 (-)
BALB/cJ MGP_BALBcJ_G0009088
miRNA gene Chr8:81828966-81829037 (-)
C3H/HeJ MGP_C3HHeJ_G0009027
miRNA gene Chr8:84747874-84747945 (-)
C57BL/6NJ MGP_C57BL6NJ_G0009328
miRNA gene Chr8:88320501-88320572 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008197
miRNA gene Chr8:75520092-75520163 (-)
CAST/EiJ MGP_CASTEiJ_G0008862
miRNA gene Chr8:84172351-84172422 (-)
CBA/J MGP_CBAJ_G0008996
miRNA gene Chr8:91422685-91422756 (-)
DBA/2J MGP_DBA2J_G0009026
miRNA gene Chr8:81360516-81360587 (-)
FVB/NJ MGP_FVBNJ_G0009044
miRNA gene Chr8:80288456-80288527 (-)
LP/J MGP_LPJ_G0009122
miRNA gene Chr8:85163790-85163861 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0009009
miRNA gene Chr8:93932338-93932409 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0009299
miRNA gene Chr8:84117582-84117653 (-)
PWK/PhJ MGP_PWKPhJ_G0008789
miRNA gene Chr8:80586332-80586403 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008631
miRNA gene Chr8:82931419-82931490 (-)
WSB/EiJ MGP_WSBEiJ_G0008957
miRNA gene Chr8:84526148-84526219 (-)



Homology
more
  • Human Ortholog
    MIR181D, microRNA 181d
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR181D, microRNA 181d
  • Synonyms
    mir-181d, MIRN181D
  • Links
    NCBI Gene ID: 574457

  • Chr Location
    chr19:13874875-13875011 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 1 genetic background
    1 phenotype from multigenic genotypes
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased elevated percentage of T cells in the spleen.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100049549 NCBI Gene Model | MGI Sequence Detail 72 C57BL/6J ±  kb
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 3
      Primer pair 2
      Other 1
    Other Database
    Links
    less
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 32
    • Earliest
      J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
    • Latest
      J:294133 Zhang M, et al., Long non-coding RNA NEAT1 inhibits oxidative stress-induced vascular endothelial cell injury by activating the miR-181d-5p/CDKN3 axis. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3129-3137

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    05/10/2022
    MGI 6.19
    The Jackson Laboratory