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Gm8909 Gene Detail
Summary
  • Symbol
    Gm8909
  • Name
    predicted gene 8909
  • Feature Type
    protein coding gene
  • IDs
    MGI:3704134
    NCBI Gene: 667977
  • Gene Overview
    MyGene.info: HLA-A
Location & Maps
more
  • Sequence Map
    Chr17:36164443-36168537 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4095 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    HLA-A, major histocompatibility complex, class I, A
  • Vertebrate Orthologs
    57
  • Human Ortholog
    HLA-A, major histocompatibility complex, class I, A
    Orthology source: HomoloGene
  • Synonyms
    Aw-33, Aw-74, HLAA
  • Links
    NCBI Gene ID: 3105
    neXtProt AC: NX_P04439, NX_P30443

  • Chr Location
    6p21.3; chr6:29942470-29945884 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human HLA-A associations

Human Disease Mouse Models
       Severe Cutaneous Adverse Reaction, Susceptibility to   OMIM: 608579
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    2
  • Gene trapped
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Gm8909
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037026 VEGA Gene Model | MGI Sequence Detail 4095 C57BL/6J ±  kb
transcript OTTMUST00000095222 VEGA | MGI Sequence Detail 1428 Not Applicable  
polypeptide OTTMUSP00000053121 VEGA | MGI Sequence Detail 396 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    20 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR027648 MHC class I alpha chain
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
References
more
  • Summaries
    All 9
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:23000 MGD Nomenclature Committee, 2/14/1995;
  • Latest
    J:161428 Gaudet P, et al., Annotation inferences using phylogenetic trees. 2010;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory