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Gm8909 Gene Detail
Summary
  • Symbol
    Gm8909
  • Name
    predicted gene 8909
  • Feature Type
    protein coding gene
  • IDs
    MGI:3704134
    NCBI Gene: 667977
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:36475335-36479429 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.97 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3704134
protein coding gene Chr17:36454704-36479490 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023669
protein coding gene Chr17:36307190-36315587 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0023595
protein coding gene Chr17:35697890-35701965 (-)
BALB/cJ MGP_BALBcJ_G0023633
protein coding gene Chr17:35436836-35441312 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0024071
protein coding gene Chr17:37964564-37968658 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0023460
protein coding gene Chr17:34238236-36688205 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023493
protein coding gene Chr17:38266218-38272363 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024117
protein coding gene Chr17:36019825-36023919 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0022426
protein coding gene Chr17:33199568-33206670 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    HLA-B, major histocompatibility complex, class I, B
  • Vertebrate Orthologs
    12
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HLA-B, major histocompatibility complex, class I, B
  • Synonyms
    AS, B-4901, HLAB
  • Links
    NCBI Gene ID: 3106
    neXtProt AC: NX_P01889
    UniProt: P01889

  • Chr Location
    6p21.33; chr6:31353866-31357245 (-)  GRCh38.p7

  • Human Ortholog
    HLA-C, major histocompatibility complex, class I, C
  • Synonyms
    D6S204, HLAC, HLA-JY3, HLC-C, MHC, PSORS1
  • Links
    NCBI Gene ID: 3107
    neXtProt AC: NX_P10321
    UniProt: P10321

  • Chr Location
    6p21.33; chr6:31268749-31272136 (-)  GRCh38.p7

  • Human Ortholog
    HLA-E, major histocompatibility complex, class I, E
  • Synonyms
    HLA-6.2, QA1
  • Links
    NCBI Gene ID: 3133
    neXtProt AC: NX_P13747
    UniProt: P13747

  • Chr Location
    6p22.1; chr6:30489406-30494205 (+)  GRCh38.p7

  • Human Ortholog
    HLA-F, major histocompatibility complex, class I, F
  • Synonyms
    CDA12, HLA-5.4, HLA-CDA12, HLAF
  • Links
    NCBI Gene ID: 3134
    neXtProt AC: NX_P30511
    UniProt: P30511

  • Chr Location
    6p22.1; chr6:29723340-29740355 (+)  GRCh38.p7

  • Human Ortholog
    HLA-G, major histocompatibility complex, class I, G
  • Synonyms
    MHC-G
  • Links
    NCBI Gene ID: 3135
    neXtProt AC: NX_P17693
    UniProt: P17693

  • Chr Location
    6p22.1; chr6:29826967-29831130 (+)  GRCh38.p7

  • Human Ortholog
    HLA-H, major histocompatibility complex, class I, H (pseudogene)
  • Synonyms
    HLAHP
  • Links
    NCBI Gene ID: 3136
    UniProt: P01893

  • Chr Location
    6p22.1; chr6:29887760-29891080 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    3 with human HLA-B,HLA-C,HLA-G associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073402 Ensembl Gene Model | MGI Sequence Detail 4095 C57BL/6J ±  kb
transcript ENSMUST00000173353 Ensembl | MGI Sequence Detail 1428 Not Applicable  
polypeptide ENSMUSP00000133663 Ensembl | MGI Sequence Detail 396 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
References
more
  • Summaries
    All 9
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
  • Latest
    J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory