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Syndig1 Gene Detail
Summary
  • Symbol
    Syndig1
  • Name
    synapse differentiation inducing 1
  • Synonyms
    SynDIG1, Tmem90b
  • Feature Type
    protein coding gene
  • IDs
    MGI:3702158
    NCBI Gene: 433485
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:149830783-150004392 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 73.80 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1231 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3702158
protein coding gene Chr2:149829211-150004392 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026623
protein coding gene Chr2:154219224-154399584 (+)
A/J MGP_AJ_G0026588
protein coding gene Chr2:147987891-148165084 (+)
AKR/J MGP_AKRJ_G0026561
protein coding gene Chr2:152227705-152407957 (+)
BALB/cJ MGP_BALBcJ_G0026598
protein coding gene Chr2:148397633-148574045 (+)
C3H/HeJ MGP_C3HHeJ_G0026341
protein coding gene Chr2:152713081-152893170 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027045
protein coding gene Chr2:158736610-158917455 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024421
protein coding gene Chr2:141902861-142077410 (+)
CAST/EiJ MGP_CASTEiJ_G0025803
protein coding gene Chr2:153052567-153233494 (+)
CBA/J MGP_CBAJ_G0026321
protein coding gene Chr2:164510733-164709999 (+)
DBA/2J MGP_DBA2J_G0026455
protein coding gene Chr2:147211482-147399923 (+)
FVB/NJ MGP_FVBNJ_G0026420
protein coding gene Chr2:145700497-145875029 (+)
LP/J MGP_LPJ_G0026560
protein coding gene Chr2:154340020-154518286 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026439
protein coding gene Chr2:168692899-168884082 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027100
protein coding gene Chr2:152227055-152409317 (+)
PWK/PhJ MGP_PWKPhJ_G0025538
protein coding gene Chr2:146905560-147087620 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025340
protein coding gene Chr2:151316505-151503620 (+)
WSB/EiJ MGP_WSBEiJ_G0025876
protein coding gene Chr2:153176755-153351713 (+)



Homology
more
  • Human Ortholog
    SYNDIG1, synapse differentiation inducing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SYNDIG1, synapse differentiation inducing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf39, DSPC2, IFITMD5, TMEM90B
  • Links
    NCBI Gene ID: 79953
    neXtProt AC: NX_Q9H7V2
    UniProt: Q9H7V2

  • Chr Location
    20p11.21; chr20:24469199-24666617 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Syndig1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 433485 NCBI Gene Model | MGI Sequence Detail 173610 C57BL/6J ±  kb
transcript NM_001363094 RefSeq | MGI Sequence Detail 2266 C57BL/6  
polypeptide A2ANU3 UniProt | EBI | MGI Sequence Detail 258 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139314
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:242651 Kim SK, et al., Strain survey and genetic analysis of vasoreactivity in mouse aorta. Physiol Genomics. 2016 Oct 07;:physiolgenomics.00054.2016

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/16/2019
MGI 6.13
The Jackson Laboratory