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Syndig1 Gene Detail
Summary
  • Symbol
    Syndig1
  • Name
    synapse differentiation inducing 1
  • Synonyms
    SynDIG1, Tmem90b
  • Feature Type
    protein coding gene
  • IDs
    MGI:3702158
    NCBI Gene: 433485
Location & Maps
more
  • Sequence Map
    Chr2:149829211-150004392 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      175182 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 73.80 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SYNDIG1, synapse differentiation inducing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SYNDIG1, synapse differentiation inducing 1
    Orthology source: HomoloGene
  • Synonyms
    C20orf39, DSPC2, IFITMD5, TMEM90B
  • Links
    NCBI Gene ID: 79953
    neXtProt AC: NX_Q9H7V2

  • Chr Location
    20p11.21; chr20:24469199-24666617 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Syndig1
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015750 VEGA Gene Model | MGI Sequence Detail 175182 C57BL/6J ±  kb
transcript OTTMUST00000037399 VEGA | MGI Sequence Detail 2050 Not Applicable  
polypeptide OTTMUSP00000016753 VEGA | MGI Sequence Detail 258 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1240 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000032430 synapse differentiation-inducing gene protein 1
  • InterPro Domains
    IPR007593 CD225/Dispanin family
Molecular
Reagents
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  • All nucleic 3
    cDNA 3

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139314
References
more
  • Summaries
    All 25
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:158601 Kalashnikova E, et al., SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development. Neuron. 2010 Jan 14;65(1):80-93
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory