Cwc22rt5 Gene Detail

Summary

• Symbol
  Cwc22rt5
• Name
  CWC22 spliceosome-associated protein, retrotransposed 5
• Synonyms
  Gm13694

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:3702064
  NCBI Gene: 668113
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr2:83809277-83811769 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, 49.33 cM

Strain
Comparison

• Strain Annotations
  6

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3702064	protein coding gene	Chr2:83809189-83812242 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025896	protein coding gene	Chr2:84612897-84615509 (+)
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0034992	protein coding gene	ChrX:92682708-92683477 (+)
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0025739	protein coding gene	Chr2:80955829-80956478 (+)
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	MGP_PWKPhJ_G0024832	protein coding gene	Chr2:80721510-80723229 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0034516	protein coding gene	ChrX:93537618-93541890 (+)
WSB/EiJ	no annotation

Homology

• Human Ortholog
  CWC22, CWC22 spliceosome associated protein

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CWC22, CWC22 spliceosome associated protein
  
• Synonyms
  EIF4GL, fSAPb, NCM
• Links
  HGNC:29322

  NCBI Gene ID: 57703

  UniProt: Q9HCG8

  
  
• Chr Location
  2q31.3; chr2:179944872-180007297 (-)  GRCh38

---

• MGI Vertebrate Homology
  Cwc22rt5 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: CWC22
• Gene Tree
  Cwc22rt5
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Targeted
  2
• Genomic Mutations
  3 involving Cwc22rt5
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  13
• RefSeq
  1
• CCDS
  CCDS50617.1

• Ensembl
  ENSMUSG00000096337 (Evidence)
• NCBI Gene
  668113

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000096337	Ensembl Gene Model | MGI Sequence Detail	2493	C57BL/6J
transcript	ENSMUST00000178533	Ensembl | MGI Sequence Detail	2493	Not Applicable
polypeptide	ENSMUSP00000135979	Ensembl | MGI Sequence Detail	830	Not Applicable

Other
Accession IDs

MGI:7466233

References

• Summaries
  All 11

  Phenotypes 5
• Earliest
  J:100298 Spitz F, et al., Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat Genet. 2005 Aug;37(8):889-93
• Latest
  J:269738 Guerreiro I, et al., Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife. 2016 Aug 1;5:e16087