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Arhgap23 Gene Detail
Summary
  • Symbol
    Arhgap23
  • Name
    Rho GTPase activating protein 23
  • Feature Type
    protein coding gene
  • IDs
    MGI:3697726
    NCBI Gene: 58996
Location & Maps
more
  • Sequence Map
    Chr11:97415533-97502402 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      86870 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 60.97 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ARHGAP23, Rho GTPase activating protein 23
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARHGAP23, Rho GTPase activating protein 23
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 57636
    neXtProt AC: NX_Q9P227

  • Chr Location
    17q12; chr17:38419286-38512392 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    138
  • Gene trapped
    133
  • Targeted
    5
  • Genomic Mutations
    1 involving Arhgap23
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002673 VEGA Gene Model | MGI Sequence Detail 86870 C57BL/6J ±  kb
transcript OTTMUST00000005237 VEGA | MGI Sequence Detail 5816 Not Applicable  
polypeptide OTTMUSP00000002485 VEGA | MGI Sequence Detail 1488 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    539 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 38

    Microarray probesets 6
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 16
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory