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Zglp1 Gene Detail
Summary
  • Symbol
    Zglp1
  • Name
    zinc finger, GATA-like protein 1
  • Synonyms
    Glp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3696042
    NCBI Gene: 100009600
Location & Maps
more
  • Sequence Map
    Chr9:21062393-21067093 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4701 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 7.70 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ZGLP1, zinc finger, GATA-like protein 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZGLP1, zinc finger, GATA-like protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GATAD3, GLP1, GLP-1
  • Links
    NCBI Gene ID: 100125288
    neXtProt AC: NX_P0C6A0

  • Chr Location
    19p13.2; chr19:10304803-10309557 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Gene trapped
    3
  • Targeted
    4
  • Incidental Mutations
Mutations result in female and male infertility due to failure of germ cell development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Literature Summary
  • Other Mouse Links
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100009600 NCBI Gene Model | MGI Sequence Detail 4701 C57BL/6J ±  kb
transcript NM_001103168 RefSeq | MGI Sequence Detail 1010 C57BL/6  
polypeptide Q1WG82 UniProt | EBI | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    7 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008039 GATA-type zinc finger protein 1
  • InterPro Domains
    IPR000679 Zinc finger, GATA-type
    IPR013088 Zinc finger, NHR/GATA-type
Molecular
Reagents
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  • Microarray probesets 1
References
more
  • Summaries
    All 17
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:116977 Li S, et al., GLP-1: a novel zinc finger protein required in somatic cells of the gonad for germ cell development. Dev Biol. 2007 Jan 1;301(1):106-16
  • Latest
    J:218062 Kim N, et al., Regulation of retinal axon growth by secreted Vax1 homeodomain protein. Elife. 2014;3:e02671

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory