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Ifi213 Gene Detail
Summary
  • Symbol
    Ifi213
  • Name
    interferon activated gene 213
  • Synonyms
    E030037K03Rik, Pydc4, Pyr-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:3695276
    NCBI Gene: 623121
  • Gene Overview
    MyGene.info: IFI16
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173566595-173599302 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 80.49 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    682 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3695276
protein coding gene Chr1:173566283-173599302 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0016788
protein coding gene Chr1:172063416-172078123 (-)
AKR/J MGP_AKRJ_G0016754
protein coding gene Chr1:177444844-177453267 (-)
BALB/cJ MGP_BALBcJ_G0016749
protein coding gene Chr1:172898566-172905761 (+)
C3H/HeJ MGP_C3HHeJ_G0016573
protein coding gene Chr1:178161737-178168225 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0014918
protein coding gene Chr1:163929132-163937235 (-)
CAST/EiJ MGP_CASTEiJ_G0016154
protein coding gene Chr1:177284916-177492106 (+)
CBA/J MGP_CBAJ_G0016547
protein coding gene Chr1:192006553-192142422 (-)
DBA/2J MGP_DBA2J_G0016654
protein coding gene Chr1:171199195-171206776 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0016726
protein coding gene Chr1:180623942-180628821 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016678
protein coding gene Chr1:199225392-199251871 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0015940
protein coding gene Chr1:170394053-170401114 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015724
protein coding gene Chr1:176429750-176436285 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Vertebrate Orthologs
    16
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
    Orthology source: HomoloGene
  • Synonyms
    IFNGIP1, PYHIN2
  • Links
    NCBI Gene ID: 3428
    neXtProt AC: NX_Q16666
    UniProt: Q16666

  • Chr Location
    1q23.1; chr1:158999968-159055155 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 623121 NCBI Gene Model | MGI Sequence Detail 32708 C57BL/6J ±  kb
transcript NM_001177349 RefSeq | MGI Sequence Detail 2687 C57BL/6  
polypeptide NP_001170821 RefSeq | MGI Sequence Detail 135 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR004020 DAPIN domain
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 4
References
more
  • Summaries
    All 19
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:190914 Brunette RL, et al., Extensive evolutionary and functional diversity among mammalian AIM2-like receptors. J Exp Med. 2012 Oct 22;209(11):1969-83
  • Latest
    J:234263 Gray EE, et al., The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA. Immunity. 2016 Aug 16;45(2):255-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory