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Aktip
Gene Detail
 Symbol
Name
ID
Aktip
thymoma viral proto-oncogene 1 interacting protein
MGI:3693832
Synonyms Ft1
Feature Type protein coding gene
Genetic Map
Chromosome 8
44.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:91112041-91134465 bp, - strand
From VEGA annotation of GRCm38

  22425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7721  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Aktip

Human
homologs
Human Homolog AKTIP, AKT interacting protein
NCBI Gene ID 64400
neXtProt AC  NX_Q9H8T0
Human Synonyms  FT1, FTS
Human Chr (Location)  16q12.2; chr16:53491280-53504411 (-)  GRCh38
Alleles
and
phenotypes
All alleles(4) : Targeted(3) Gene trapped(1)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process apoptotic process, early endosome to late endosome transport, ...
Component cytoplasm, FHF complex, ...
Function acid-amino acid ligase activity
Expression
Literature Summary: (6 records)
Data Summary: Results (214)    Tissues (83)    Images (30)
Theiler Stages: 14, 15, 16, 18, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 180
Northern blot 26
RT-PCR 8
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(16) Genomic(3) cDNA(12) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000031747 (Evidence)
Ensembl Gene ModelENSMUSG00000031667 (Evidence)
Entrez Gene14339 (Evidence)
NIA Mouse Gene IndexU030088
Consensus CDS ProjectCCDS22519.1
International Mouse Knockout Project StatusAktip
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031747 VEGA Gene Model | MGI Sequence Detail 22425 C57BL/6J ±  kb
transcript OTTMUST00000078640 VEGA | MGI Sequence Detail 2153 Not Applicable 
polypeptide OTTMUSP00000041846 VEGA | MGI Sequence Detail 292 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(12) UniProt(4)
Polymorphisms RFLP(1) : SNPs within 2kb(284 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
InterPro IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Protein Ontology PR:000003914 AKT-interacting protein
References (Earliest) J:20159 van der Hoeven F, et al., Programmed cell death is affected in the novel mouse mutant Fused toes (Ft). Development. 1994 Sep;120(9):2601-7
(Latest) J:173702 Kim B, et al., The fused toes locus is essential for somatic-germ cell interactions that foster germ cell maturation in developing gonads in mice. Biol Reprod. 2011 May;84(5):1024-32
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory