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Krt83 Gene Detail
Summary
  • Symbol
    Krt83
  • Name
    keratin 83
  • Synonyms
    5430421N21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3690448
    NCBI Gene: 100126226
  • Gene Overview
    MyGene.info: KRT83
Location & Maps
more
  • Sequence Map
    Chr15:101485131-101491512 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6382 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.90 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    KRT83, keratin 83
  • Vertebrate Orthologs
    6
  • Human Ortholog
    KRT83, keratin 83
    Orthology source: HomoloGene
  • Synonyms
    Hb-3, HB3, KRTHB3
  • Links
    NCBI Gene ID: 3889
    neXtProt AC: NX_P78385

  • Chr Location
    12q13; chr12:52314301-52321398 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human KRT83 associations

Human Disease Mouse Models
       Monilethrix; MNLIX   OMIM: 158000
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    4
  • Genomic Mutations
    4 involving Krt83
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033745 VEGA Gene Model | MGI Sequence Detail 6382 C57BL/6J ±  kb
transcript OTTMUST00000085039 VEGA | MGI Sequence Detail 1756 Not Applicable  
polypeptide OTTMUSP00000045897 VEGA | MGI Sequence Detail 479 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    28 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001664 Intermediate filament protein
    IPR018039 Intermediate filament protein, conserved site
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
Molecular
Reagents
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  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 18
    Diseases 1
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory