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Try10
Gene Detail
Symbol

Name
ID
Try10 (Interim)
trypsin 10
MGI:3687012
Synonyms
trypsinogen 10
Feature Type
protein coding gene
Genetic Map
Chromosome 6
19.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:41354105-41357914 bp, + strand
From VEGA annotation of GRCm38

  3810 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134623  Vertebrate Homology Class
1 human; 1 mouse; 2 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: PRSS1
Protein SuperFamily: trypsin
Gene Tree: Try10

Human
homologs
PRSS1, protease, serine, 1 (trypsin 1)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 5644
neXtProt AC: NX_P07477

Human Synonyms: TRP1, TRY1, TRY4, TRYP1

Human Chr (Location): 7q34; chr7:142740235-142753076 (+)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human PRSS1

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Try10 interacts with 8 markers (Mir325, Mir452, Mir455, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process digestion, proteolysis
Component blood microparticle, extracellular exosome, ...
Function serine-type endopeptidase activity
Expression
cDNA source data(48)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase try10    NEW 
Molecular
reagents
All nucleic(48) cDNA(48)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000051419 (Evidence)
Ensembl Gene Model ENSMUSG00000071521 (Evidence)
Entrez Gene 436522 (Evidence)
UniGene 443385
Consensus CDS Project CCDS20046.1
International Mouse Phenotyping Consortium Status Try10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051419 VEGA Gene Model | MGI Sequence Detail 3810 C57BL/6J ±  kb
transcript OTTMUST00000129976 VEGA | MGI Sequence Detail 860 Not Applicable 
polypeptide OTTMUSP00000069738 VEGA | MGI Sequence Detail 246 Not Applicable 

For the selected sequences
All sequences(15) RefSeq(3) UniProt(1)
Polymorphisms
SNPs within 2kb(31 from dbSNP Build 137)    SNPs within 2kb including multiple locations(39)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
References
(Earliest) J:53168 Bairoch A, et al., SWISS-PROT Annotated protein sequence database. Database Release. 1999;
(Latest) J:57747 MGI Genome Annotation Group and UniGene Staff, MGI-UniGene Interconnection Effort. Database Download. 2015;
All references(13)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory