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Tvp23a Gene Detail
Summary
  • Symbol
    Tvp23a
  • Name
    trans-golgi network vesicle protein 23A
  • Synonyms
    Fam18a
  • Feature Type
    protein coding gene
  • IDs
    MGI:3665441
    NCBI Gene: 383103
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:10238421-10265226 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 5.61 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1598 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3665441
 protein coding gene Chr16:10237397-10265251 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022507
 protein coding gene Chr16:7213195-7246064 (-)
A/J MGP_AJ_G0022469
 protein coding gene Chr16:6820880-6847652 (-)
AKR/J MGP_AKRJ_G0022445
 protein coding gene Chr16:7141300-7168097 (-)
BALB/cJ MGP_BALBcJ_G0022473
 protein coding gene Chr16:6958298-6984968 (-)
C3H/HeJ MGP_C3HHeJ_G0022240
 protein coding gene Chr16:7222513-7249292 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022922
 protein coding gene Chr16:7371407-7398211 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020443
 protein coding gene Chr16:6962085-6996072 (-)
CAST/EiJ MGP_CASTEiJ_G0021767
 protein coding gene Chr16:7224481-7256719 (-)
CBA/J MGP_CBAJ_G0022209
 protein coding gene Chr16:7684436-7711206 (-)
DBA/2J MGP_DBA2J_G0022340
 protein coding gene Chr16:6834317-6861108 (-)
FVB/NJ MGP_FVBNJ_G0022316
 protein coding gene Chr16:6814221-6841003 (-)
LP/J MGP_LPJ_G0022408
 protein coding gene Chr16:7173515-7205539 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022338
 protein coding gene Chr16:7418862-7445784 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022935
 protein coding gene Chr16:7088730-7115512 (-)
PWK/PhJ MGP_PWKPhJ_G0021507
 protein coding gene Chr16:7028603-7060634 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021337
 protein coding gene Chr16:7143129-7175587 (-)
WSB/EiJ MGP_WSBEiJ_G0021815
 protein coding gene Chr16:7153679-7191522 (-)



Homology
more
  • Human Ortholog
    TVP23A, trans-golgi network vesicle protein 23 homolog A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TVP23A, trans-golgi network vesicle protein 23 homolog A
  • Synonyms
    FAM18A, YDR084C
  • Links
    NCBI Gene ID: 780776
    UniProt: A6NH52

  • Chr Location
    16p13.13; chr16:10757318-10818794 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050908 Ensembl Gene Model | MGI Sequence Detail 26806 C57BL/6J ±  kb
transcript ENSMUST00000051118 Ensembl | MGI Sequence Detail 3315 Not Applicable  
polypeptide ENSMUSP00000052922 Ensembl | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR008564 Golgi apparatus membrane protein TVP23-like
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:126685 Bussink AP, et al., Evolution of Mammalian chitinase(-like) members of family 18 glycosyl hydrolases. Genetics. 2007 Oct;177(2):959-70
  • Latest
    J:344350 Griffin EN, et al., RREB1 regulates neuronal proteostasis and the microtubule network. Sci Adv. 2024 Jan 12;10(2):eadh3929
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory