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Igflr1 Gene Detail
Summary
  • Symbol
    Igflr1
  • Name
    IGF-like family receptor 1
  • Synonyms
    F630003I17Rik, Tmem149
  • Feature Type
    protein coding gene
  • IDs
    MGI:3655979
    NCBI Gene: 101883
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30565427-30567962 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 18.62 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3655979
protein coding gene Chr7:30565427-30567962 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032030
protein coding gene Chr7:29573323-29575858 (+)
A/J MGP_AJ_G0032007
protein coding gene Chr7:28770951-28773480 (+)
AKR/J MGP_AKRJ_G0031940
protein coding gene Chr7:29502085-29504614 (+)
BALB/cJ MGP_BALBcJ_G0032014
protein coding gene Chr7:28958385-28960914 (+)
C3H/HeJ MGP_C3HHeJ_G0031733
protein coding gene Chr7:29961044-29963579 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032480
protein coding gene Chr7:30522746-30525281 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029530
protein coding gene Chr7:29797960-29800523 (+)
CAST/EiJ MGP_CASTEiJ_G0031067
protein coding gene Chr7:23213792-23216323 (+)
CBA/J MGP_CBAJ_G0031699
protein coding gene Chr7:31988721-31991256 (+)
DBA/2J MGP_DBA2J_G0031851
protein coding gene Chr7:28499364-28501895 (+)
FVB/NJ MGP_FVBNJ_G0031808
protein coding gene Chr7:28630235-28632770 (+)
LP/J MGP_LPJ_G0031932
protein coding gene Chr7:29880404-29882935 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031844
protein coding gene Chr7:31224521-31227058 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032508
protein coding gene Chr7:29012988-29015521 (+)
PWK/PhJ MGP_PWKPhJ_G0030791
protein coding gene Chr7:23536720-23539255 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030626
protein coding gene Chr7:20020966-20023481 (+)
WSB/EiJ MGP_WSBEiJ_G0031177
protein coding gene Chr7:29400103-29402623 (+)



Homology
more
  • Human Ortholog
    IGFLR1, IGF like family receptor 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    IGFLR1, IGF like family receptor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TMEM149
  • Links
    NCBI Gene ID: 79713
    neXtProt AC: NX_Q9H665
    UniProt: Q9H665

  • Chr Location
    19q13.12; chr19:35739250-35742450 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 101883 NCBI Gene Model | MGI Sequence Detail 2536 C57BL/6J ±  kb
transcript NM_145580 RefSeq | MGI Sequence Detail 1192 C57BL/6  
polypeptide Q3U4N7 UniProt | EBI | MGI Sequence Detail 345 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR011029 Death-like domain superfamily
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 5
References
more
  • Summaries
    All 28
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:83847 Shepard J, et al., Characterization of U2AF(6), a splicing factor related to U2AF(35). Mol Cell Biol. 2002 Jan;22(1):221-30
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory