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Krtap4-8 Gene Detail
Summary
  • Symbol
    Krtap4-8
  • Name
    keratin associated protein 4-8
  • Synonyms
    OTTMUSG00000002541
  • Feature Type
    protein coding gene
  • IDs
    MGI:3652306
    NCBI Gene: 665992
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:99670840-99671469 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.12 cM
Strain
Comparison
more
  • SNPs within 2kb
    9 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3652306
 protein coding gene Chr11:99670548-99671530 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019115
 protein coding gene Chr11:102477562-102479782 (-)
A/J MGP_AJ_G0019086
 protein coding gene Chr11:98158783-98177699 (-)
AKR/J MGP_AKRJ_G0019055
 protein coding gene Chr11:101204524-101207187 (-)
BALB/cJ MGP_BALBcJ_G0019057
 protein coding gene Chr11:98685482-98686344 (-)
C3H/HeJ MGP_C3HHeJ_G0018871
 protein coding gene Chr11:101363373-101364340 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019507
 protein coding gene Chr11:105614048-105614790 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017139
 protein coding gene Chr11:95676803-95695930 (-)
CAST/EiJ MGP_CASTEiJ_G0018425
 protein coding gene Chr11:102386879-102397250 (-)
CBA/J MGP_CBAJ_G0018844
 protein coding gene Chr11:110022029-110022906 (-)
DBA/2J MGP_DBA2J_G0018950
 protein coding gene Chr11:97733888-97735112 (-)
FVB/NJ MGP_FVBNJ_G0018942
 protein coding gene Chr11:97236590-97240424 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0018968
 protein coding gene Chr11:109683822-109684955 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019548
 protein coding gene Chr11:101569674-101571510 (-)
PWK/PhJ MGP_PWKPhJ_G0018193
 protein coding gene Chr11:98805108-98826791 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017981
 protein coding gene Chr11:101270990-101271900 (-)
WSB/EiJ MGP_WSBEiJ_G0018476
 protein coding gene Chr11:101540196-101541178 (-)



Homology
more
  • Human Ortholog
    KRTAP4-3, keratin associated protein 4-3
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP4-3, keratin associated protein 4-3
  • Synonyms
    KAP4.3
  • Links
    NCBI Gene ID: 85290
    neXtProt AC: NX_Q9BYR4
    UniProt: Q9BYR4

  • Chr Location
    17q21.2; chr17:41167231-41168221 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 665992 NCBI Gene Model | MGI Sequence Detail 630 C57BL/6J ±  kb
transcript NM_001085547 RefSeq | MGI Sequence Detail 630 Not Specified  
polypeptide NP_001079016 RefSeq | MGI Sequence Detail 209 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
References
more
  • Summaries
    All 17
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory