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Klf18 Gene Detail
Summary
  • Symbol
    Klf18
  • Name
    Kruppel-like transcription factor 18
  • Synonyms
    Gm12845
Location &
Maps
more
  • Sequence Map
    Chr4:117581771-117583168 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.46 cM
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651666
protein coding gene Chr4:117581609-117584069 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028653
protein coding gene Chr4:118712043-118714503 (+)
A/J MGP_AJ_G0028614
protein coding gene Chr4:114137656-114140116 (+)
AKR/J MGP_AKRJ_G0028564
protein coding gene Chr4:116635809-116638269 (+)
BALB/cJ MGP_BALBcJ_G0028635
protein coding gene Chr4:114759328-114761788 (+)
C3H/HeJ MGP_C3HHeJ_G0028349
protein coding gene Chr4:118217820-118220280 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029076
protein coding gene Chr4:123282181-123284641 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026360
protein coding gene Chr4:108166507-108168939 (+)
CAST/EiJ MGP_CASTEiJ_G0027783
protein coding gene Chr4:115425957-115428417 (+)
CBA/J MGP_CBAJ_G0028316
protein coding gene Chr4:126656443-126658903 (+)
DBA/2J MGP_DBA2J_G0028464
protein coding gene Chr4:114755716-114758176 (+)
FVB/NJ MGP_FVBNJ_G0028432
protein coding gene Chr4:113271619-113274079 (+)
LP/J MGP_LPJ_G0028566
protein coding gene Chr4:118897847-118900307 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028459
protein coding gene Chr4:131569659-131572119 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029113
protein coding gene Chr4:117781488-117783948 (+)
PWK/PhJ MGP_PWKPhJ_G0027509
protein coding gene Chr4:111573164-111575624 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027332
protein coding gene Chr4:114092402-114094865 (+)
WSB/EiJ MGP_WSBEiJ_G0027862
protein coding gene Chr4:117673995-117676455 (+)



Homology
more
  • Human Ortholog
    KLF18, KLF transcription factor 18
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLF18, KLF transcription factor 18
  • Links
    NCBI Gene ID: 105378952
    UniProt: A0A0U1RQI7

  • Chr Location
    chr1:44137821-44141631 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Klf18
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 100416740 NCBI Gene Model | MGI Sequence Detail 1398 C57BL/6J ±  kb
For the selected sequence
References
more
  • Summaries
    All 9
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
  • Latest
    J:161428 Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas, Annotation inferences using phylogenetic trees. 2010;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory