Gm11937 Gene Detail

Summary

• Symbol
  Gm11937
• Name
  predicted gene 11937

• Feature Type
  protein coding gene
• IDs
  MGI:3651231
  NCBI Gene: 100041488
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr11:99609794-99610189 bp, - strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 62.95 cM

Strain
Comparison

• SNPs within 2kb
  9 from dbSNP Build 142
• Strain Annotations
  11

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3651231	protein coding gene	Chr11:99609794-99610431 (-)
129S1/SvImJ	no annotation
A/J	MGP_AJ_G0019074	protein coding gene	Chr11:97984837-97986753 (-)
AKR/J	MGP_AKRJ_G0019044	protein coding gene	Chr11:101019917-101020283 (-)
BALB/cJ	no annotation
C3H/HeJ	MGP_C3HHeJ_G0018860	protein coding gene	Chr11:101178913-101180248 (-)
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0017131	protein coding gene	Chr11:95539448-95539858 (-)
CAST/EiJ	MGP_CASTEiJ_G0018417	protein coding gene	Chr11:102176729-102179515 (-)
CBA/J	MGP_CBAJ_G0018833	protein coding gene	Chr11:109819671-109820066 (-)
DBA/2J	no annotation
FVB/NJ	MGP_FVBNJ_G0018930	protein coding gene	Chr11:97055087-97055573 (-)
LP/J	MGP_LPJ_G0019010	protein coding gene	Chr11:102759306-102760402 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018957	protein coding gene	Chr11:109484533-109485019 (-)
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0018465	protein coding gene	Chr11:101352488-101352974 (-)

Homology

• Human Ortholog
  KRTAP2-3, keratin associated protein 2-3

• Vertebrate Orthologs
  21

• Human Ortholog
  KRTAP2-3, keratin associated protein 2-3
  Orthology source: HomoloGene
• Synonyms
  KAP2.3, KAP2.4, KRTAP2.3, KRTAP2-4, KRTAP2.4
• Links
  HGNC:18906

  NCBI Gene ID: 730755

  neXtProt AC: NX_P0C7H8, NX_Q9BYR9

  UniProt: P0C7H8

  
  
• Chr Location
  chr17:41059240-41060092 (-)  GRCh38.p7

---

• Human Ortholog
  KRTAP2-4, keratin associated protein 2-4
  Orthology source: HomoloGene
• Synonyms
  KAP2.1B, KAP2.3, KAP2.4, KRTAP2-3, KRTAP2.3, KRTAP2.4
• Links
  HGNC:18891

  NCBI Gene ID: 85294

  neXtProt AC: NX_P0C7H8, NX_Q9BYR9

  UniProt: Q9BYR9

  
  
• Chr Location
  17q21.2; chr17:41065116-41065879 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 41961
  2 human;3 mouse;3 rat;2 chimpanzee;4 cattle;4 dog;3 macaque, rhesus
  
• HCOP
  human homology predictions: KRTAP2-3, KRTAP2-4
• Gene Tree
  Gm11937
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Genomic Mutations
  2 involving Gm11937
• Find Mice (IMSR)
  2 strains or lines available

Expression

• Assay Results
  631

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  18
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS48910.1

• Ensembl
  ENSMUSG00000058725 (Evidence)
• NCBI Gene
  100041488

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000058725	Ensembl Gene Model | MGI Sequence Detail	396	C57BL/6J
transcript	ENSMUST00000076478	Ensembl | MGI Sequence Detail	396	Not Applicable
polypeptide	ENSMUSP00000075802	Ensembl | MGI Sequence Detail	131	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR002494 Keratin-associated protein

Molecular
Reagents

• 
  

  Microarray probesets 1

References

• Summaries
  All 15

  Phenotypes 6
• Earliest
  J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
• Latest
  J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75

TSS for Gm11937:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr110692	Chr11:99610427-99610434 (-)	-242 bp
Tssr110691	Chr11:99610417-99610422 (-)	-231 bp
Tssr3667	Chr11:99610246-99610253 (-)	-61 bp