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Krtap2-21 Gene Detail
Summary
  • Symbol
    Krtap2-21
  • Name
    keratin associated protein 2-21
  • Synonyms
    Gm11937
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651231
    NCBI Gene: 100041488
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99500620-99501015 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 62.95 cM
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651231
 protein coding gene Chr11:99500620-99501257 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0019074
 protein coding gene Chr11:97984837-97986753 (-)
AKR/J MGP_AKRJ_G0019044
 protein coding gene Chr11:101019917-101020283 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0018860
 protein coding gene Chr11:101178913-101180248 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0017131
 protein coding gene Chr11:95539448-95539858 (-)
CAST/EiJ MGP_CASTEiJ_G0018417
 protein coding gene Chr11:102176729-102179515 (-)
CBA/J MGP_CBAJ_G0018833
 protein coding gene Chr11:109819671-109820066 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0018930
 protein coding gene Chr11:97055087-97055573 (-)
LP/J MGP_LPJ_G0019010
 protein coding gene Chr11:102759306-102760402 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018957
 protein coding gene Chr11:109484533-109485019 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0018465
 protein coding gene Chr11:101352488-101352974 (-)



Homology
more
  • Human Ortholog
    KRTAP2-1, keratin associated protein 2-1
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP2-1, keratin associated protein 2-1
  • Synonyms
    KAP2.1A, KRTAP2.1A
  • Links
    NCBI Gene ID: 81872
    UniProt: Q9BYU5

  • Chr Location
    17q21.2; chr17:41046541-41047316 (-)  GRCh38
  • Human Ortholog
    KRTAP2-2, keratin associated protein 2-2
  • Synonyms
    KAP2.1, KAP2.2, KRTAP2-1, KRTAP2.1A, KRTAP2.1B
  • Links
    NCBI Gene ID: 728279

  • Chr Location
    17q21.2; chr17:41054498-41055230 (-)  GRCh38
  • Human Ortholog
    KRTAP2-3, keratin associated protein 2-3
  • Synonyms
    KAP2.3, KAP2.4, KRTAP2.3, KRTAP2-4, KRTAP2.4
  • Links
    NCBI Gene ID: 730755
    UniProt: P0C7H8

  • Chr Location
    chr17:41059240-41060114 (-)  GRCh38
  • Human Ortholog
    KRTAP2-4, keratin associated protein 2-4
  • Synonyms
    KAP2.1B, KAP2.3, KAP2.4, KRTAP2-3, KRTAP2.3, KRTAP2.4
  • Links
    NCBI Gene ID: 85294
    UniProt: Q9BYR9

  • Chr Location
    17q21.2; chr17:41065116-41065879 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058725 Ensembl Gene Model | MGI Sequence Detail 396 C57BL/6J ±  kb
transcript ENSMUST00000076478 Ensembl | MGI Sequence Detail 396 Not Applicable  
polypeptide ENSMUSP00000075802 Ensembl | MGI Sequence Detail 131 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
    IPR052154 Keratin-associated protein type 2
Molecular
Reagents
less

  • Microarray probesets 1
Other
Accession IDs
less
MGI:7580725
References
more
  • Summaries
    All 16
    Phenotypes 7
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:357457 Kumar V, et al., Keratin-dependent thymic stromal lymphopoietin expression suggests a link between skin blistering and atopic disease. J Allergy Clin Immunol. 2016;138(5):1461-1464
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory