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Wfdc17 Gene Detail
Summary
  • Symbol
    Wfdc17
  • Name
    WAP four-disulfide core domain 17
  • Synonyms
    Gm11428
  • Feature Type
    protein coding gene
  • IDs
    MGI:3649773
    NCBI Gene: 100034251
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:83704056-83706269 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 51.22 cM
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649773
protein coding gene Chr11:83703991-83706269 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018858
protein coding gene Chr11:85084811-85087087 (+)
A/J MGP_AJ_G0018825
protein coding gene Chr11:81837232-81839508 (+)
AKR/J MGP_AKRJ_G0018795
protein coding gene Chr11:84265444-84267722 (+)
BALB/cJ MGP_BALBcJ_G0018798
protein coding gene Chr11:82234623-82236900 (+)
C3H/HeJ MGP_C3HHeJ_G0018612
protein coding gene Chr11:84318185-84320461 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019250
protein coding gene Chr11:87658934-87661211 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016883
protein coding gene Chr11:78940366-78942654 (+)
CAST/EiJ MGP_CASTEiJ_G0018167
protein coding gene Chr11:84937178-84941409 (+)
CBA/J MGP_CBAJ_G0018583
protein coding gene Chr11:91428352-91430628 (+)
DBA/2J MGP_DBA2J_G0018691
protein coding gene Chr11:81427916-81430194 (+)
FVB/NJ MGP_FVBNJ_G0018680
protein coding gene Chr11:80902814-80905091 (+)
LP/J MGP_LPJ_G0018761
protein coding gene Chr11:85620416-85622692 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018707
protein coding gene Chr11:91594473-91596750 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019290
protein coding gene Chr11:84537958-84540235 (+)
PWK/PhJ MGP_PWKPhJ_G0017936
protein coding gene Chr11:82178997-82181274 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017728
protein coding gene Chr11:84080586-84082875 (+)
WSB/EiJ MGP_WSBEiJ_G0018218
protein coding gene Chr11:84388728-84391005 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Wfdc17
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100034251 NCBI Gene Model | MGI Sequence Detail 2214 C57BL/6J ±  kb
transcript NM_001081957 RefSeq | MGI Sequence Detail 485 Not Specified  
polypeptide NP_001075426 RefSeq | MGI Sequence Detail 76 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR036645 Elafin-like superfamily
    IPR008197 WAP-type 'four-disulfide core' domain
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory