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Trav7-2 Gene Detail
Summary
  • Symbol
    Trav7-2
  • Name
    T cell receptor alpha variable 7-2
  • Synonyms
    Gm13952
  • Feature Type
    gene segment
  • IDs
    MGI:3649607
    NCBI Gene: 634132
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr14:53628090-53628593 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 27.35 cM
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649607
 gene segment Chr14:53628090-53628599 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002552
 gene segment Chr14:47322090-47322597 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0002510
 gene segment Chr14:47972273-47974627 (+)
BALB/cJ MGP_BALBcJ_G0002491
 gene segment Chr14:45623099-45623606 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0002618
 gene segment Chr14:48813699-48814206 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0002428
 gene segment Chr14:43882874-43883380 (+)
CBA/J MGP_CBAJ_G0002481
 gene segment Chr14:51094554-51095165 (+)
DBA/2J MGP_DBA2J_G0002464
 gene segment Chr14:45274445-45274952 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0002521
 gene segment Chr14:47363399-47363896 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002449
 gene segment Chr14:49737424-49737931 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002660
 gene segment Chr14:47225146-47225761 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0002343
 gene segment Chr14:42544969-42545480 (+)
WSB/EiJ MGP_WSBEiJ_G0002458
 gene segment Chr14:46829818-46830324 (+)



Homology
more
  • Human Ortholog
    TRAV12-1, T cell receptor alpha variable 12-1
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRAV12-1, T cell receptor alpha variable 12-1
  • Synonyms
    TCRAV12S1, TCRAV2S3, TRAV121
  • Links
    NCBI Gene ID: 28674
    UniProt: A0A0B4J245

  • Chr Location
    14q11.2; chr14:21841240-21841774 (+)  GRCh38
  • Human Ortholog
    TRAV12-2, T cell receptor alpha variable 12-2
  • Synonyms
    TCRAV12S2, TCRAV2S1, TRAV122
  • Links
    NCBI Gene ID: 28673
    UniProt: A0A075B6T6

  • Chr Location
    14q11.2; chr14:21887857-21888502 (+)  GRCh38
  • Human Ortholog
    TRAV12-3, T cell receptor alpha variable 12-3
  • Synonyms
    TCRAV12S3, TCRAV2S2, TRAV123
  • Links
    NCBI Gene ID: 28672
    UniProt: A0A0B4J271

  • Chr Location
    14q11.2; chr14:21965451-21966061 (+)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    19
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 634132 NCBI Gene Model | MGI Sequence Detail 504 C57BL/6J ±  kb
polypeptide Q5R1I3 UniProt | EBI | MGI Sequence Detail 112 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
References
more
  • Summaries
    All 10
    Gene Ontology 2
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
  • Latest
    J:271745 Takeda Y, et al., TRAV7-2*02 Expressing CD8(+) T Cells Are Responsible for Palladium Allergy. Int J Mol Sci. 2017 May 31;18(6):1162
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory