Trav7-5 Gene Detail

Summary

• Symbol
  Trav7-5
• Name
  T cell receptor alpha variable 7-5

• Feature Type
  gene segment
• IDs
  MGI:3648929
  NCBI Gene: 630061
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr14:53768243-53768770 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 27.41 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  53 from dbSNP Build 142
• Strain Annotations
  13

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3648929	gene segment	Chr14:53768243-53768770 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0002546	gene segment	Chr14:47110935-47111462 (+)
A/J	no annotation
AKR/J	MGP_AKRJ_G0002500	gene segment	Chr14:47661966-47662493 (+)
BALB/cJ	MGP_BALBcJ_G0002507	gene segment	Chr14:46097499-46098026 (+)
C3H/HeJ	MGP_C3HHeJ_G0002479	gene segment	Chr14:47441157-47441684 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0002635	gene segment	Chr14:49357994-49358520 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0002448	gene segment	Chr14:44139112-44139639 (+)
CBA/J	MGP_CBAJ_G0002474	gene segment	Chr14:50803954-50804481 (+)
DBA/2J	MGP_DBA2J_G0002485	gene segment	Chr14:45763140-45763667 (+)
FVB/NJ	MGP_FVBNJ_G0002496	gene segment	Chr14:45327137-45327664 (+)
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0002649	gene segment	Chr14:46970964-46971491 (+)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0002350	gene segment	Chr14:42866542-42867069 (+)
WSB/EiJ	MGP_WSBEiJ_G0002484	gene segment	Chr14:47321932-47322459 (+)

Homology

• Human Ortholog
  TRAV12-1, T cell receptor alpha variable 12-1

• Vertebrate Orthologs
  9

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TRAV12-1, T cell receptor alpha variable 12-1
  
• Synonyms
  TCRAV12S1, TCRAV2S3, TRAV121
• Links
  HGNC:12105

  NCBI Gene ID: 28674

  UniProt: A0A0B4J245

  
  
• Chr Location
  14q11.2; chr14:21841240-21841774 (+)  GRCh38

---

• Human Ortholog
  TRAV12-2, T cell receptor alpha variable 12-2
  
• Synonyms
  TCRAV12S2, TCRAV2S1, TRAV122
• Links
  HGNC:12106

  NCBI Gene ID: 28673

  UniProt: A0A075B6T6

  
  
• Chr Location
  14q11.2; chr14:21887857-21888502 (+)  GRCh38

---

• Human Ortholog
  TRAV12-3, T cell receptor alpha variable 12-3
  
• Synonyms
  TCRAV12S3, TCRAV2S2, TRAV123
• Links
  HGNC:12107

  NCBI Gene ID: 28672

  UniProt: A0A0B4J271

  
  
• Chr Location
  14q11.2; chr14:21965451-21966061 (+)  GRCh38

---

• MGI Vertebrate Homology
  Trav7-5 stringent orthology
  3 human;1 mouse;6 zebrafish
  
• HCOP
  vertebrate homology predictions: TRAV12-1, TRAV12-2, TRAV12-3
• Gene Tree
  Trav7-5
  

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  20
• RefSeq
  2
• UniProt
  1

• Ensembl
  ENSMUSG00000106620 (Evidence)
• NCBI Gene
  630061

Representative Sequences			Length	Strain/Species
genomic	630061	NCBI Gene Model | MGI Sequence Detail	528	C57BL/6J
polypeptide	A0A0G2JFX6	UniProt | EBI | MGI Sequence Detail	112	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain

References

• Summaries
  All 9

  Gene Ontology 1
• Earliest
  J:82725 Fan L, et al., Antigen presentation by keratinocytes directs autoimmune skin disease. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3386-91
• Latest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Trav7-5:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125481	Chr14:53768203-53768221 (+)	-31 bp