Eno1b Gene Detail

Summary

• Symbol
  Eno1b
• Name
  enolase 1B, retrotransposed
• Synonyms
  Gm5506

• Feature Type
  protein coding gene
• IDs
  MGI:3648653
  NCBI Gene: 433182
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr18:48178402-48181446 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 18, 25.33 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  239 from dbSNP Build 142
• Strain Annotations
  17

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3648653	protein coding gene	Chr18:48178402-48181479 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027884	protein coding gene	Chr3:133693983-133695429 (-)
A/J	MGP_AJ_G0027842	protein coding gene	Chr3:128994547-128996076 (-)
AKR/J	MGP_AKRJ_G0027807	protein coding gene	Chr3:132348953-132350597 (-)
BALB/cJ	MGP_BALBcJ_G0027855	protein coding gene	Chr3:128848488-128850188 (-)
C3H/HeJ	MGP_C3HHeJ_G0027584	protein coding gene	Chr3:132756262-132757768 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0024829	protein coding gene	Chr18:48558732-48561429 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0021101	protein coding gene	Chr17:12329748-12334957 (+)
CAST/EiJ	MGP_CASTEiJ_G0020268	protein coding gene	Chr14:6955871-6966107 (-)
CBA/J	MGP_CBAJ_G0027560	protein coding gene	Chr3:143060080-143061579 (-)
DBA/2J	MGP_DBA2J_G0020835	protein coding gene	Chr14:6727486-6729010 (-)
FVB/NJ	MGP_FVBNJ_G0020817	protein coding gene	Chr14:6644572-6646026 (-)
LP/J	MGP_LPJ_G0027810	protein coding gene	Chr3:135171416-135173388 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020843	protein coding gene	Chr14:7492953-7494637 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028356	protein coding gene	Chr3:132028317-132029901 (-)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0018923	protein coding gene	Chr12:98745834-98748178 (-)
WSB/EiJ	MGP_WSBEiJ_G0022483	protein coding gene	Chr17:14923467-14925092 (+)

Homology

• Human Ortholog
  ENO1, enolase 1

• Vertebrate Orthologs
  6

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  ENO1, enolase 1
  
• Synonyms
  ENO1-IT1, ENO1L1, HEL-S-17, MPB1, NNE, PPH
• Links
  HGNC:3350

  NCBI Gene ID: 2023

  UniProt: P06733

  
  
• Chr Location
  1p36.23; chr1:8861000-8879190 (-)  GRCh38

---

• MGI Vertebrate Homology
  Eno1b stringent orthology
  1 human;1 mouse;4 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: ENO1
• Protein SuperFamily
  Enolase
• Gene Tree
  Eno1b
  

Human Diseases

• Diseases
  1 with human ENO1 associations

				Human Disease	Mouse Models
				Alzheimer's disease IDs Alzheimer's disease       DOID:10652 ICD10CM:G30 ICD9CM:331.0 KEGG:05010 MESH:D000544 NCI:C2866 UMLS_CUI:C0002395

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  1
• Spontaneous
  1
• Genomic Mutations
  1 involving Eno1b
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  19 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  2
• Literature Summary
  2

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  27
• RefSeq
  2
• CCDS
  CCDS50285.1

• Ensembl
  ENSMUSG00000059040 (Evidence)
• NCBI Gene
  433182

Representative Sequences			Length	Strain/Species
genomic	433182	NCBI Gene Model | MGI Sequence Detail	3045	C57BL/6J
transcript	NM_001025388	RefSeq | MGI Sequence Detail	1758	C57BL/6
polypeptide	NP_001020559	RefSeq | MGI Sequence Detail	434	C57BL/6

Molecular
Reagents

• All nucleic 3

  cDNA 3

  
  

  Microarray probesets 1

References

• Summaries
  All 13

  Developmental Gene Expression 2

  Phenotypes 2
• Earliest
  J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
• Latest
  J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67

TSS for Eno1b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr150975	Chr18:48178396-48178415 (+)	4 bp
Tssr150976	Chr18:48178421-48178422 (+)	20 bp
Tssr150977	Chr18:48179712-48179713 (+)	1,311 bp