Ndufs6b Pseudogene Detail

Summary

• Symbol
  Ndufs6b
• Name
  NADH:ubiquinone oxidoreductase subunit S6B
• Synonyms
  Gm6415

• Feature Type
  pseudogene
  BioType Conflict
  
• IDs
  MGI:3648526
  NCBI Gene: 623286
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr7:80811145-80811492 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 45.71 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  165 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3648526	pseudogene	Chr7:80811021-80811494 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0013945	pseudogene	Chr7:83196148-83196495 (-)
A/J	MGP_AJ_G0013964	pseudogene	Chr7:81241215-81241562 (-)
AKR/J	MGP_AKRJ_G0013898	pseudogene	Chr7:83029195-83029542 (-)
BALB/cJ	MGP_BALBcJ_G0013921	pseudogene	Chr7:80894726-80895073 (-)
C3H/HeJ	MGP_C3HHeJ_G0013756	pseudogene	Chr7:83649111-83649458 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0014354	pseudogene	Chr7:86459725-86460072 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0012203	pseudogene	Chr7:83727219-83727566 (-)
CAST/EiJ	MGP_CASTEiJ_G0013413	pseudogene	Chr7:74561374-74561721 (-)
CBA/J	MGP_CBAJ_G0013735	pseudogene	Chr7:89349426-89349773 (-)
DBA/2J	MGP_DBA2J_G0013814	pseudogene	Chr7:79777194-79777541 (-)
FVB/NJ	MGP_FVBNJ_G0013817	pseudogene	Chr7:79706018-79706365 (-)
LP/J	MGP_LPJ_G0013889	pseudogene	Chr7:84431013-84431360 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0013843	pseudogene	Chr7:89433917-89434264 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0014314	pseudogene	Chr7:82444478-82444825 (-)
PWK/PhJ	MGP_PWKPhJ_G0013229	pseudogene	Chr7:72983666-72984013 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0012992	pseudogene	Chr7:69451275-69451620 (-)
WSB/EiJ	MGP_WSBEiJ_G0013476	pseudogene	Chr7:82803838-82804185 (-)

Homology

• Human Ortholog
  NDUFS6, NADH:ubiquinone oxidoreductase subunit S6

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  NDUFS6, NADH:ubiquinone oxidoreductase subunit S6
  
• Synonyms
  CI-13kA, CI-13kD-A, CI13KDA, MC1DN9
• Links
  HGNC:7713

  NCBI Gene ID: 4726

  UniProt: O75380

  
  
• Chr Location
  5p15.33; chr5:1801407-1816048 (+)  GRCh38

---

• MGI Vertebrate Homology
  Ndufs6b stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: NDUFS6
• Gene Tree
  Ndufs6b
  

Human Diseases

• Diseases
  2 with human NDUFS6 associations

				Human Disease	Mouse Models
				cervical cancer IDs cervical cancer       DOID:4362 DOID:4361 ICD10CM:C53 ICD9CM:180 ICD9CM:180.9 MESH:D002583 NCI:C2940 NCI:C9311 OMIM:603956 UMLS_CUI:C0007847 UMLS_CUI:C0007873
				nuclear type mitochondrial complex I deficiency 9 IDs nuclear type mitochondrial complex I deficiency 9       DOID:0112073 OMIM:618232

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  11 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Radiation induced
  2
• Genomic Mutations
  3 involving Ndufs6b
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  23
• RefSeq
  2

• Ensembl
  ENSMUSG00000083820 (Evidence)
• NCBI Gene
  623286

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000083820	Ensembl Gene Model | MGI Sequence Detail	348	C57BL/6J
transcript	ENSMUST00000118488	Ensembl | MGI Sequence Detail	348	Not Applicable
polypeptide	XP_036009552	RefSeq | MGI Sequence Detail	116	C57BL/6J

Other
Accession IDs

MGI:6154850

References

• Summaries
  All 15

  Phenotypes 11
• Earliest
  J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
• Latest
  J:123187 Cohen-Barak O, et al., Stem cell transplantation demonstrates that Sox6 represses epsilon y globin expression in definitive erythropoiesis of adult mice. Exp Hematol. 2007 Mar;35(3):358-67

TSS for Ndufs6b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr73320	Chr7:80811492-80811503 (-)	-6 bp