About   Help   FAQ
Cyp2a22 Gene Detail
Summary
  • Symbol
    Cyp2a22
  • Name
    cytochrome P450, family 2, subfamily a, polypeptide 22
  • Synonyms
    EG233005
  • Feature Type
    protein coding gene
  • IDs
    MGI:3648316
    NCBI Gene: 233005
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:26931631-26939384 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 15.65 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    65 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3648316
protein coding gene Chr7:26931631-26939413 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031892
protein coding gene Chr7:25521954-25531303 (-)
A/J MGP_AJ_G0031873
protein coding gene Chr7:25032427-25039886 (+)
AKR/J MGP_AKRJ_G0031802
protein coding gene Chr7:25657093-25665207 (+)
BALB/cJ MGP_BALBcJ_G0031878
protein coding gene Chr7:25228410-25237400 (+)
C3H/HeJ MGP_C3HHeJ_G0031599
protein coding gene Chr7:25942424-25950776 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032342
protein coding gene Chr7:26482427-26489066 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030935
protein coding gene Chr7:19350629-19370228 (+)
CBA/J MGP_CBAJ_G0031564
protein coding gene Chr7:27600323-27615099 (+)
DBA/2J MGP_DBA2J_G0031716
protein coding gene Chr7:24836487-24844821 (+)
FVB/NJ MGP_FVBNJ_G0031672
protein coding gene Chr7:24898592-24913103 (+)
LP/J MGP_LPJ_G0031796
protein coding gene Chr7:25914859-25924234 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031707
protein coding gene Chr7:27219160-27225977 (+)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0030659
protein coding gene Chr7:19799254-19808764 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030492
protein coding gene Chr7:16197265-16205548 (+)
WSB/EiJ MGP_WSBEiJ_G0031042
protein coding gene Chr7:25488543-25496515 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000091867 Ensembl Gene Model | MGI Sequence Detail 7754 C57BL/6J ±  kb
transcript ENSMUST00000170227 Ensembl | MGI Sequence Detail 1796 Not Applicable  
polypeptide ENSMUSP00000128030 Ensembl | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR008067 Cytochrome P450, E-class, group I, CYP2A-like
    IPR036396 Cytochrome P450 superfamily
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 14
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
  • Latest
    J:216691 Li L, et al., Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from a novel Cyp2abfgs-null mouse. Carcinogenesis. 2014 Nov;35(11):2584-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/12/2019
MGI 6.14
The Jackson Laboratory