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Slc38a6 Gene Detail
Summary
  • Symbol
    Slc38a6
  • Name
    solute carrier family 38, member 6
  • Synonyms
    EG625098
  • Feature Type
    protein coding gene
  • IDs
    MGI:3648156
    NCBI Gene: 625098
Location & Maps
more
  • Sequence Map
    Chr12:73286779-73354049 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      67271 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 30.42 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC38A6, solute carrier family 38 member 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC38A6, solute carrier family 38 member 6
    Orthology source: HomoloGene
  • Synonyms
    NAT-1, SNAT6
  • Links
    NCBI Gene ID: 145389
    neXtProt AC: NX_Q8IZM9

  • Chr Location
    14q23.1; chr14:60981114-61083733 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Targeted
    3
  • Genomic Mutations
    1 involving Slc38a6
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032835 VEGA Gene Model | MGI Sequence Detail 67271 C57BL/6J ±  kb
transcript OTTMUST00000081781 VEGA | MGI Sequence Detail 3032 Not Applicable  
polypeptide OTTMUSP00000043793 VEGA | MGI Sequence Detail 457 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    518 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000031782 sodium-coupled neutral amino acid transporter 6
  • InterPro Domains
    IPR013057 Amino acid transporter, transmembrane domain
Molecular
Reagents
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  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
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MGI:2145022
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:224717 Bagchi S, et al., Histological analysis of SLC38A6 (SNAT6) expression in mouse brain shows selective expression in excitatory neurons with high expression in the synapses. PLoS One. 2014;9(4):e95438

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory