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Slc38a6 Gene Detail
Summary
  • Symbol
    Slc38a6
  • Name
    solute carrier family 38, member 6
  • Synonyms
    EG625098
  • Feature Type
    protein coding gene
  • IDs
    MGI:3648156
    NCBI Gene: 625098
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:73286779-73354049 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 30.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    518 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3648156
protein coding gene Chr12:73286739-73361998 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019836
protein coding gene Chr12:73182205-73250156 (+)
A/J MGP_AJ_G0019794
protein coding gene Chr12:70445760-70511656 (+)
AKR/J MGP_AKRJ_G0019769
protein coding gene Chr12:72580664-72644843 (+)
BALB/cJ MGP_BALBcJ_G0019774
protein coding gene Chr12:70925872-70989555 (+)
C3H/HeJ MGP_C3HHeJ_G0019579
protein coding gene Chr12:73010995-73080097 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020226
protein coding gene Chr12:75460203-75531671 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017844
protein coding gene Chr12:67888657-67951891 (+)
CAST/EiJ MGP_CASTEiJ_G0019131
protein coding gene Chr12:67808345-67879402 (+)
CBA/J MGP_CBAJ_G0019549
protein coding gene Chr12:78336238-78413232 (+)
DBA/2J MGP_DBA2J_G0019665
protein coding gene Chr12:70340617-70403290 (+)
FVB/NJ MGP_FVBNJ_G0019652
protein coding gene Chr12:69188738-69251458 (+)
LP/J MGP_LPJ_G0019737
protein coding gene Chr12:73206528-73269007 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019691
protein coding gene Chr12:81470530-81538217 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020261
protein coding gene Chr12:72065986-72133809 (+)
PWK/PhJ MGP_PWKPhJ_G0018896
protein coding gene Chr12:64659007-64749777 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018691
protein coding gene Chr12:66489015-66558759 (+)
WSB/EiJ MGP_WSBEiJ_G0019182
protein coding gene Chr12:72656934-72723601 (+)



Homology
more
  • Human Ortholog
    SLC38A6, solute carrier family 38 member 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC38A6, solute carrier family 38 member 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NAT-1, SNAT6
  • Links
    NCBI Gene ID: 145389
    neXtProt AC: NX_Q8IZM9
    UniProt: Q8IZM9

  • Chr Location
    14q23.1; chr14:60981114-61083733 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044712 Ensembl Gene Model | MGI Sequence Detail 67271 C57BL/6J ±  kb
transcript ENSMUST00000140523 Ensembl | MGI Sequence Detail 3032 Not Applicable  
polypeptide ENSMUSP00000120810 Ensembl | MGI Sequence Detail 457 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000031782 probable sodium-coupled neutral amino acid transporter 6
  • InterPro Domains
    IPR013057 Amino acid transporter, transmembrane domain
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145022
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory