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Defb18 Gene Detail
Summary
  • Symbol
    Defb18
  • Name
    defensin beta 18
  • Synonyms
    EG654460
  • Feature Type
    protein coding gene
  • IDs
    MGI:3648148
    NCBI Gene: 654460
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:18236473-18237443 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 5.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    22 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3648148
protein coding gene Chr1:18236473-18237443 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015865
protein coding gene Chr1:15824763-15825733 (-)
A/J MGP_AJ_G0015846
protein coding gene Chr1:15611764-15612734 (-)
AKR/J MGP_AKRJ_G0015805
protein coding gene Chr1:15595018-15595988 (-)
BALB/cJ MGP_BALBcJ_G0015802
protein coding gene Chr1:15297999-15298969 (-)
C3H/HeJ MGP_C3HHeJ_G0015636
protein coding gene Chr1:15679366-15680336 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016256
protein coding gene Chr1:16514067-16515037 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013977
protein coding gene Chr1:14029748-14030715 (-)
CAST/EiJ MGP_CASTEiJ_G0015217
protein coding gene Chr1:15752342-15753313 (-)
CBA/J MGP_CBAJ_G0015609
protein coding gene Chr1:16867291-16868261 (-)
DBA/2J MGP_DBA2J_G0015708
protein coding gene Chr1:15188733-15189703 (-)
FVB/NJ MGP_FVBNJ_G0015713
protein coding gene Chr1:14967150-14968120 (-)
LP/J MGP_LPJ_G0015780
protein coding gene Chr1:16020526-16021496 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015732
protein coding gene Chr1:17719127-17720230 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016303
protein coding gene Chr1:15566928-15567898 (-)
PWK/PhJ MGP_PWKPhJ_G0015001
protein coding gene Chr1:14938641-14939611 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014782
protein coding gene Chr1:15698801-15699788 (-)
WSB/EiJ MGP_WSBEiJ_G0015280
protein coding gene Chr1:15557452-15558422 (-)



Homology
more
  • Human Ortholog
    DEFB113, defensin beta 113
  • Vertebrate Orthologs
    5
  • Human Ortholog
    DEFB113, defensin beta 113
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DEFB-13
  • Links
    NCBI Gene ID: 245927
    neXtProt AC: NX_Q30KQ7
    UniProt: Q30KQ7

  • Chr Location
    6p12.3; chr6:49968677-49969625 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 654460 NCBI Gene Model | MGI Sequence Detail 971 C57BL/6J ±  kb
transcript NM_001039123 RefSeq | MGI Sequence Detail 258 Not Specified  
polypeptide Q30KP5 UniProt | EBI | MGI Sequence Detail 85 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 15
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/07/2019
MGI 6.14
The Jackson Laboratory