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Fam186b Gene Detail
Summary
  • Symbol
    Fam186b
  • Name
    family with sequence similarity 186, member B
  • Synonyms
    EG545136
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647604
    NCBI Gene: 545136
  • Gene Overview
    MyGene.info: FAM186B
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:99168899-99193769 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.11 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647604
protein coding gene Chr15:99168899-99199656 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022327
protein coding gene Chr15:101094519-101115879 (-)
A/J MGP_AJ_G0022285
protein coding gene Chr15:97077400-97094780 (-)
AKR/J MGP_AKRJ_G0022261
protein coding gene Chr15:100075049-100093202 (-)
BALB/cJ MGP_BALBcJ_G0022291
protein coding gene Chr15:97264183-97280848 (-)
C3H/HeJ MGP_C3HHeJ_G0022059
protein coding gene Chr15:100133909-100150976 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022736
protein coding gene Chr15:104873115-104890803 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020262
protein coding gene Chr15:92974419-92991385 (-)
CAST/EiJ MGP_CASTEiJ_G0021583
protein coding gene Chr15:100988581-101006393 (-)
CBA/J MGP_CBAJ_G0022028
protein coding gene Chr15:108430764-108446838 (-)
DBA/2J MGP_DBA2J_G0022155
protein coding gene Chr15:96520223-96536451 (-)
FVB/NJ MGP_FVBNJ_G0022135
protein coding gene Chr15:95505019-95522855 (-)
LP/J MGP_LPJ_G0022226
protein coding gene Chr15:101244694-101266407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022155
protein coding gene Chr15:112370167-112387183 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022751
protein coding gene Chr15:100167523-100183602 (-)
PWK/PhJ MGP_PWKPhJ_G0021322
protein coding gene Chr15:96652536-96669139 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021157
protein coding gene Chr15:100019199-100035625 (-)
WSB/EiJ MGP_WSBEiJ_G0021634
protein coding gene Chr15:100700656-100716559 (-)



Homology
more
  • Human Ortholog
    FAM186B, family with sequence similarity 186 member B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM186B, family with sequence similarity 186 member B
  • Synonyms
    C12orf25
  • Links
    NCBI Gene ID: 84070
    neXtProt AC: NX_Q8IYM0
    UniProt: Q8IYM0

  • Chr Location
    12q13.12; chr12:49582875-49605710 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078907 Ensembl Gene Model | MGI Sequence Detail 24871 C57BL/6J ±  kb
transcript ENSMUST00000109100 Ensembl | MGI Sequence Detail 3187 Not Applicable  
polypeptide ENSMUSP00000104728 Ensembl | MGI Sequence Detail 943 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 1
    Phenotypes 27
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory