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Fam186b Gene Detail
Summary
  • Symbol
    Fam186b
  • Name
    family with sequence similarity 186, member B
  • Synonyms
    EG545136
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647604
    NCBI Gene: 545136
  • Gene Overview
    MyGene.info: FAM186B
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:99271018-99295885 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.11 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    157 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647604
protein coding gene Chr15:99271018-99295888 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022327
protein coding gene Chr15:101094519-101115879 (-)
A/J MGP_AJ_G0022285
protein coding gene Chr15:97077400-97094780 (-)
AKR/J MGP_AKRJ_G0022261
protein coding gene Chr15:100075049-100093202 (-)
BALB/cJ MGP_BALBcJ_G0022291
protein coding gene Chr15:97264183-97280848 (-)
C3H/HeJ MGP_C3HHeJ_G0022059
protein coding gene Chr15:100133909-100150976 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022736
protein coding gene Chr15:104873115-104890803 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020262
protein coding gene Chr15:92974419-92991385 (-)
CAST/EiJ MGP_CASTEiJ_G0021583
protein coding gene Chr15:100988581-101006393 (-)
CBA/J MGP_CBAJ_G0022028
protein coding gene Chr15:108430764-108446838 (-)
DBA/2J MGP_DBA2J_G0022155
protein coding gene Chr15:96520223-96536451 (-)
FVB/NJ MGP_FVBNJ_G0022135
protein coding gene Chr15:95505019-95522855 (-)
LP/J MGP_LPJ_G0022226
protein coding gene Chr15:101244694-101266407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022155
protein coding gene Chr15:112370167-112387183 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022751
protein coding gene Chr15:100167523-100183602 (-)
PWK/PhJ MGP_PWKPhJ_G0021322
protein coding gene Chr15:96652536-96669139 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021157
protein coding gene Chr15:100019199-100035625 (-)
WSB/EiJ MGP_WSBEiJ_G0021634
protein coding gene Chr15:100700656-100716559 (-)



Homology
more
  • Human Ortholog
    FAM186B, family with sequence similarity 186 member B
  • Vertebrate Orthologs
    7
  • Human Ortholog
    FAM186B, family with sequence similarity 186 member B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C12orf25
  • Links
    NCBI Gene ID: 84070
    neXtProt AC: NX_Q8IYM0
    UniProt: Q8IYM0

  • Chr Location
    12q13.12; chr12:49582875-49605710 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 545136 NCBI Gene Model | MGI Sequence Detail 24868 C57BL/6J ±  kb
transcript NM_001081254 RefSeq | MGI Sequence Detail 3187 Not Specified  
polypeptide NP_001074723 RefSeq | MGI Sequence Detail 943 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR039332 Protein FAM186A/FAM186B
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 35
    Diseases 1
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory