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Fam186b Gene Detail
Summary
  • Symbol
    Fam186b
  • Name
    family with sequence similarity 186, member B
  • Synonyms
    EG545136
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647604
    NCBI Gene: 545136
  • Gene Overview
    MyGene.info: FAM186B
Location & Maps
more
  • Sequence Map
    Chr15:99271018-99287180 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16163 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.11 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    FAM186B, family with sequence similarity 186 member B
  • Vertebrate Orthologs
    7
  • Human Ortholog
    FAM186B, family with sequence similarity 186 member B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C12orf25
  • Links
    NCBI Gene ID: 84070
    neXtProt AC: NX_Q8IYM0

  • Chr Location
    12q13.12; chr12:49582875-49605650 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Fam186b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078907 Ensembl Gene Model | MGI Sequence Detail 16163 C57BL/6J ±  kb
transcript ENSMUST00000109100 Ensembl | MGI Sequence Detail 3187 Not Applicable  
polypeptide ENSMUSP00000104728 Ensembl | MGI Sequence Detail 943 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    157 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 15
    Diseases 1
    Gene Ontology 1
    Phenotypes 24
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory