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Gm6614 Gene Detail
Summary
  • Symbol
    Gm6614
  • Name
    predicted gene 6614
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647159
    NCBI Gene: 625716
  • Gene Overview
    MyGene.info: SLCO1A2
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:141971845-142011414 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 73.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    412 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647159
protein coding gene Chr6:141971833-142012263 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031457
protein coding gene Chr6:146763020-146804374 (-)
A/J MGP_AJ_G0031432
protein coding gene Chr6:140978537-141019331 (-)
AKR/J MGP_AKRJ_G0031360
protein coding gene Chr6:145178662-145218139 (-)
BALB/cJ MGP_BALBcJ_G0031439
protein coding gene Chr6:140768997-140808751 (-)
C3H/HeJ MGP_C3HHeJ_G0031161
protein coding gene Chr6:145227363-145266763 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031901
protein coding gene Chr6:150763865-150805381 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030529
protein coding gene Chr6:144797730-144854567 (-)
CBA/J MGP_CBAJ_G0031121
protein coding gene Chr6:156507165-156549000 (-)
DBA/2J MGP_DBA2J_G0031278
protein coding gene Chr6:139781894-139822027 (-)
FVB/NJ MGP_FVBNJ_G0031229
protein coding gene Chr6:138575691-138614155 (-)
LP/J MGP_LPJ_G0031362
protein coding gene Chr6:146900200-146939388 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031269
protein coding gene Chr6:160415715-160456115 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031933
protein coding gene Chr6:145006306-145047336 (-)
PWK/PhJ MGP_PWKPhJ_G0030256
protein coding gene Chr6:138297738-138338740 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030080
protein coding gene Chr6:143222742-143264128 (-)
WSB/EiJ MGP_WSBEiJ_G0030622
protein coding gene Chr6:145655289-145699757 (-)



Homology
more
  • Human Ortholog
    SLCO1A2, solute carrier organic anion transporter family member 1A2
  • Vertebrate Orthologs
    2
  • Human Ortholog
    SLCO1A2, solute carrier organic anion transporter family member 1A2
    Orthology source: HGNC
  • Synonyms
    OATP, OATP1A2, OATP-A, SLC21A3
  • Links
    NCBI Gene ID: 6579
    neXtProt AC: NX_P46721
    UniProt: P46721

  • Chr Location
    12p12.1; chr12:21264600-21403657 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079263 Ensembl Gene Model | MGI Sequence Detail 39570 C57BL/6J ±  kb
transcript ENSMUST00000181628 Ensembl | MGI Sequence Detail 2364 Not Applicable  
polypeptide ENSMUSP00000137967 Ensembl | MGI Sequence Detail 670 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 15
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:163765 van de Steeg E, et al., Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs. J Clin Invest. 2010 Aug 2;120(8):2942-52
  • Latest
    J:273941 Slijepcevic D, et al., Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice. Hepatology. 2017 Nov;66(5):1631-1643

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory