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Fscb Gene Detail
Summary
  • Symbol
    Fscb
  • Name
    fibrous sheath CABYR binding protein
  • Synonyms
    EG623046
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646964
    NCBI Gene: 623046
  • Gene Overview
    MyGene.info: FSCB
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr12:64471330-64474690 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3361 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 26.96 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    FSCB, fibrous sheath CABYR binding protein
  • Vertebrate Orthologs
    2
  • Human Ortholog
    FSCB, fibrous sheath CABYR binding protein
    Orthology source: HGNC
  • Synonyms
    C14orf155
  • Links
    NCBI Gene ID: 84075
    neXtProt AC: NX_Q5H9T9
    UniProt: Q5H9T9

  • Chr Location
    14q21.2; chr14:44504149-44507296 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043060 Ensembl Gene Model | MGI Sequence Detail 3361 C57BL/6J ±  kb
transcript ENSMUST00000059833 Ensembl | MGI Sequence Detail 3361 Not Applicable  
polypeptide ENSMUSP00000051554 Ensembl | MGI Sequence Detail 1062 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    30 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 14
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:128382 Li YF, et al., FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesis. J Biol Chem. 2007 Nov 23;282(47):34104-19
  • Latest
    J:243457 Zhang X, et al., FSCB phosphorylation regulates mouse spermatozoa capacitation through suppressing SUMOylation of ROPN1/ROPN1L. Am J Transl Res. 2016;8(6):2776-82

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory