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Fignl2 Gene Detail
Summary
  • Symbol
    Fignl2
  • Name
    fidgetin-like 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646919
    NCBI Gene: 668225
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:101050194-101078567 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646919
protein coding gene Chr15:101050192-101078584 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022363
protein coding gene Chr15:103075115-103079328 (-)
A/J MGP_AJ_G0022325
protein coding gene Chr15:99014540-99018747 (-)
AKR/J MGP_AKRJ_G0022301
protein coding gene Chr15:102023456-102027661 (-)
BALB/cJ MGP_BALBcJ_G0022329
protein coding gene Chr15:99108550-99113025 (-)
C3H/HeJ MGP_C3HHeJ_G0022099
protein coding gene Chr15:102116390-102120593 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022777
protein coding gene Chr15:106922596-106928403 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020302
protein coding gene Chr15:94740243-94744457 (-)
CAST/EiJ MGP_CASTEiJ_G0021624
protein coding gene Chr15:102954291-102958509 (-)
CBA/J MGP_CBAJ_G0022068
protein coding gene Chr15:110609589-110613792 (-)
DBA/2J MGP_DBA2J_G0022195
protein coding gene Chr15:98342798-98347003 (-)
FVB/NJ MGP_FVBNJ_G0022174
protein coding gene Chr15:97386031-97390388 (-)
LP/J MGP_LPJ_G0022266
protein coding gene Chr15:103215731-103219938 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022195
protein coding gene Chr15:114329268-114333473 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022791
protein coding gene Chr15:102042171-102046377 (-)
PWK/PhJ MGP_PWKPhJ_G0021363
protein coding gene Chr15:98491350-98495587 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021195
protein coding gene Chr15:101938488-101949342 (-)
WSB/EiJ MGP_WSBEiJ_G0021674
protein coding gene Chr15:102662065-102666271 (-)



Homology
more
  • Human Ortholog
    FIGNL2, fidgetin like 2
  • Vertebrate Orthologs
    5
  • Human Ortholog
    FIGNL2, fidgetin like 2
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 401720
    neXtProt AC: NX_A6NMB9
    UniProt: A6NMB9

  • Chr Location
    12q13.13; chr12:51817892-51848753 (-)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Fignl2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000095440 Ensembl Gene Model | MGI Sequence Detail 28374 C57BL/6J ±  kb
transcript ENSMUST00000213610 Ensembl | MGI Sequence Detail 4462 Not Applicable  
polypeptide ENSMUSP00000150618 Ensembl | MGI Sequence Detail 644 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR003959 ATPase, AAA-type, core
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Diseases 1
    Gene Ontology 2
    Phenotypes 19
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory