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Trim5 Gene Detail
Summary
  • Symbol
    Trim5
  • Name
    tripartite motif-containing 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646853
    NCBI Gene: 667823
  • Gene Overview
    MyGene.info: TRIM5
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:104263386-104288094 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 55.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646853
protein coding gene Chr7:104263386-104288254 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032713
protein coding gene Chr7:107487990-107504575 (-)
A/J MGP_AJ_G0032688
protein coding gene Chr7:104673998-104689743 (-)
AKR/J MGP_AKRJ_G0032621
protein coding gene Chr7:107299130-107313240 (-)
BALB/cJ MGP_BALBcJ_G0032698
protein coding gene Chr7:104405926-104422301 (-)
C3H/HeJ MGP_C3HHeJ_G0032409
protein coding gene Chr7:107553360-107569654 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033192
protein coding gene Chr7:111555269-111623840 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030188
protein coding gene Chr7:106765939-106780224 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0032377
protein coding gene Chr7:115465613-115479973 (-)
DBA/2J MGP_DBA2J_G0032531
protein coding gene Chr7:103009098-103023915 (-)
FVB/NJ MGP_FVBNJ_G0032484
protein coding gene Chr7:102718373-102733964 (-)
LP/J MGP_LPJ_G0032624
protein coding gene Chr7:108816383-108833380 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032516
protein coding gene Chr7:116942008-116960104 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033221
protein coding gene Chr7:106482851-106501389 (-)
PWK/PhJ MGP_PWKPhJ_G0031452
protein coding gene Chr7:96006091-96025537 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031296
protein coding gene Chr7:93626321-93635690 (-)
WSB/EiJ MGP_WSBEiJ_G0031853
protein coding gene Chr7:107144827-107163570 (-)



Homology
more
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TRIM5, tripartite motif containing 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RNF88, TRIM5alpha
  • Links
    NCBI Gene ID: 85363
    neXtProt AC: NX_Q9C035
    UniProt: Q9C035

  • Chr Location
    11p15.4; chr11:5590906-5685109 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060441 Ensembl Gene Model | MGI Sequence Detail 24709 C57BL/6J ±  kb
transcript ENSMUST00000098179 Ensembl | MGI Sequence Detail 3655 Not Applicable  
polypeptide ENSMUSP00000095781 Ensembl | MGI Sequence Detail 497 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:248997 Boon AC, et al., Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice. J Virol. 2009 Oct;83(20):10417-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory