Cyp2c53-ps Pseudogene Detail

Summary

• Symbol
  Cyp2c53-ps
• Name
  cytochrome P450, family 2, subfamily c, polypeptide 53, pseudogene
• Synonyms
  EG638988

• Feature Type
  pseudogene
  BioType Conflict
  
• IDs
  MGI:3646306
  NCBI Gene: 638988
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr19:39217698-39263181 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 19, 33.87 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  821 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3646306	pseudogene	Chr19:39217698-39263429 (+)
129S1/SvImJ	ENSMUSG00200032753	pseudogene	Chr19:36015339-36068397 (+)
A/J	ENSMUSG00195012207	pseudogene	Chr19:36113070-36166131 (+)
AKR/J	ENSMUSG00220019299	pseudogene	Chr19:35997426-36034305 (+)
BALB/cJ	ENSMUSG00180034907	pseudogene	Chr19:36441001-36494061 (+)
C3H/HeJ	ENSMUSG00175043491	pseudogene	Chr19:35858979-35907618 (+)
C57BL/6NJ	ENSMUSG00215031817	pseudogene	Chr19:35887113-35942045 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005015970	pseudogene	Chr19:35491889-35527523 (+)
CBA/J	ENSMUSG00210038292	pseudogene	Chr19:35938240-35989821 (+)
DBA/2J	ENSMUSG00185034331	pseudogene	Chr19:36458397-36509979 (+)
FVB/NJ	ENSMUSG00205053422	pseudogene	Chr17:50137615-50164595 (+)
JF1/MsJ	ENSUMUG00000049087	pseudogene	Chr19:36635853-36692631 (+)
LP/J	ENSMUSG00230037033	pseudogene	Chr19:37285079-37338136 (+)
NOD/ShiLtJ	ENSMUSG00190011626	pseudogene	Chr19:35848639-35895642 (+)
NZO/HlLtJ	ENSMUSG00225044754	pseudogene	Chr19:40834885-40887948 (+)
PWK/PhJ	ENSLUMG00010001449	pseudogene	Chr19:35993020-36033846 (+)
SPRET/EiJ	ENSMSPG00010023695	pseudogene	Chr19:35717260-35744412 (+)
WSB/EiJ	ENSIUOG00005040600	pseudogene	Chr19:35360028-35386500 (+)

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Genomic Mutations
  2 involving Cyp2c53-ps
• Find Mice (IMSR)
  0 strains or lines available

Expression

• cDNA Data
  1

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  30
• RefSeq
  1

• Ensembl
  ENSMUSG00000093610 (Evidence), ENSMUSG00000121373 (Evidence)
• NCBI Gene
  638988

Representative Sequences			Length	Strain/Species
genomic	638988	NCBI Gene Model | MGI Sequence Detail	45484	C57BL/6J
transcript	NR_033614	RefSeq | MGI Sequence Detail	1443	C57BL/6

Molecular
Reagents

• All nucleic 1

  cDNA 1

References

• Summaries
  All 12

  Phenotypes 6
• Earliest
  J:241121 Scheer N, et al., Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines. Mol Pharmacol. 2012 Dec;82(6):1022-9
• Latest
  J:341617 Zhang J, et al., CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 Jul;37(7):e23009

TSS for Cyp2c53-ps:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr156322	Chr19:39217706-39217710 (+)	10 bp