Cyp2c53-ps Pseudogene Detail

Summary

• Symbol
  Cyp2c53-ps
• Name
  cytochrome P450, family 2, subfamily c, polypeptide 53, pseudogene
• Synonyms
  EG638988

• Feature Type
  pseudogene
  BioType Conflict
  
• IDs
  MGI:3646306
  NCBI Gene: 638988
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr19:39217698-39263181 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 19, 33.87 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  142 from dbSNP Build 142
• Strain Annotations
  17

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3646306	pseudogene	Chr19:39217698-39263429 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0039808	pseudogene	Chr19:38366726-38393584 (+)
A/J	MGP_AJ_G0039807	pseudogene	Chr19:36477923-36508740 (+)
AKR/J	MGP_AKRJ_G0039734	pseudogene	Chr19:37693146-37738353 (+)
BALB/cJ	MGP_BALBcJ_G0039781	pseudogene	Chr19:36583113-36612349 (+)
C3H/HeJ	MGP_C3HHeJ_G0039437	pseudogene	Chr19:37788135-37822232 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0040347	pseudogene	Chr19:39402843-39436606 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0038549	pseudogene	Chr19:37584889-37618629 (+)
CBA/J	MGP_CBAJ_G0039406	pseudogene	Chr19:41301187-41354673 (+)
DBA/2J	MGP_DBA2J_G0039607	pseudogene	Chr19:36306098-36338604 (+)
FVB/NJ	MGP_FVBNJ_G0039564	pseudogene	Chr19:36134115-36175779 (+)
LP/J	MGP_LPJ_G0039642	pseudogene	Chr19:38420056-38454387 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0039565	pseudogene	Chr19:41021542-41054121 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0040450	pseudogene	Chr19:37798440-37828970 (+)
PWK/PhJ	MGP_PWKPhJ_G0038228	pseudogene	Chr19:36163079-36204385 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0037971	pseudogene	Chr19:36588432-36602309 (+)
WSB/EiJ	MGP_WSBEiJ_G0038784	pseudogene	Chr19:37901711-37933135 (+)

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Genomic Mutations
  2 involving Cyp2c53-ps
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  26
• RefSeq
  1

• Ensembl
  ENSMUSG00000093610 (Evidence), ENSMUSG00000121373 (Evidence)
• NCBI Gene
  638988

Representative Sequences			Length	Strain/Species
genomic	638988	NCBI Gene Model | MGI Sequence Detail	45484	C57BL/6J
transcript	NR_033614	RefSeq | MGI Sequence Detail	1443	C57BL/6

Molecular
Reagents

• All nucleic 1

  cDNA 1

References

• Summaries
  All 11

  Phenotypes 6
• Earliest
  J:241121 Scheer N, et al., Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines. Mol Pharmacol. 2012 Dec;82(6):1022-9
• Latest
  J:341617 Zhang J, et al., CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 Jul;37(7):e23009

TSS for Cyp2c53-ps:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr156322	Chr19:39217706-39217710 (+)	10 bp