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Ceacam3 Gene Detail
Summary
  • Symbol
    Ceacam3
  • Name
    CEA cell adhesion molecule 3
  • Synonyms
    cea12, EG384557, Psg24
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646296
    NCBI Gene: 384557
  • Member of
    Cea cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:16884207-16898178 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.15 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    527 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646296
 protein coding gene Chr7:16884122-16898891 (+)
129S1/SvImJ ENSMUSG00200038825
 protein coding gene Chr7:10255623-10269640 (+)
A/J ENSMUSG00195051608
 protein coding gene Chr7:10726065-10740117 (+)
AKR/J ENSMUSG00220025632
 protein coding gene Chr7:9019605-9033569 (+)
BALB/cJ ENSMUSG00180050397
 protein coding gene Chr7:10641866-10655912 (+)
C3H/HeJ ENSMUSG00175044806
 protein coding gene Chr7:11120401-11134421 (+)
C57BL/6NJ ENSMUSG00215053994
 protein coding gene Chr7:10382994-10396964 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029255
 protein coding gene Chr7:16168707-16182320 (+)
CAST/EiJ ENSTCUG00005051925
 protein coding gene Chr7:11125816-11139848 (+)
CBA/J ENSMUSG00210051132
 protein coding gene Chr7:10347405-10361422 (+)
DBA/2J ENSMUSG00185050851
 protein coding gene Chr7:13868007-13881988 (+)
FVB/NJ ENSMUSG00205049769
 protein coding gene Chr7:10753553-10767532 (+)
JF1/MsJ ENSUMUG00000019979
 protein coding gene Chr7:17154817-17168860 (+)
LP/J ENSMUSG00230042140
 protein coding gene Chr7:18080485-18092929 (+)
NOD/ShiLtJ ENSMUSG00190037084
 protein coding gene Chr7:7188592-7202557 (+)
NZO/HlLtJ ENSMUSG00225053231
 protein coding gene Chr7:15322018-15336010 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010045987
 protein coding gene Chr7:9898513-9912142 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CEACAM21, CEA cell adhesion molecule 21
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEACAM21, CEA cell adhesion molecule 21
  • Synonyms
    R29124_1
  • Links
    NCBI Gene ID: 90273
    UniProt: Q3KPI0

  • Chr Location
    19q13.2; chr19:41549518-41586844 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    1
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000053228 Ensembl Gene Model | MGI Sequence Detail 13972 C57BL/6J ±  kb
    transcript ENSMUST00000108491 Ensembl | MGI Sequence Detail 3261 Not Applicable  
    polypeptide ENSMUSP00000104131 Ensembl | MGI Sequence Detail 706 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR050831 Carcinoembryonic antigen-related cell adhesion
      IPR003599 Immunoglobulin domain subtype
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR003598 Immunoglobulin subtype 2
      IPR013106 Immunoglobulin V-set domain
    Molecular
    Reagents
    less
    • All nucleic 1
      cDNA 1

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:1891356
    References
    more
    • Summaries
      All 25
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:98494 McLellan AS, et al., Structure and evolution of the mouse pregnancy-specific glycoprotein (Psg) gene locus. BMC Genomics. 2005 Jan 12;6(1):4
    • Latest
      J:392403 Chen X, et al., ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal-Fetal Interface. Adv Sci (Weinh). 2025 Nov;12(42):e05491
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory