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Esp1 Gene Detail
Summary
  • Symbol
    Esp1
  • Name
    exocrine gland secreted peptide 1
  • Synonyms
    ESP1, Gm6084
  • Feature Type
    protein coding gene
  • IDs
    MGI:3645915
    NCBI Gene: 619517
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:41038011-41042673 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    47 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645915
 protein coding gene Chr17:41038011-41042673 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023759
 protein coding gene Chr17:41531631-41536288 (+)
A/J MGP_AJ_G0023717
 protein coding gene Chr17:40593414-40598076 (+)
AKR/J MGP_AKRJ_G0023688
 protein coding gene Chr17:40762556-40767216 (+)
BALB/cJ MGP_BALBcJ_G0023721
 protein coding gene Chr17:40517256-40521718 (+)
C3H/HeJ MGP_C3HHeJ_G0023485
 protein coding gene Chr17:41452320-41456980 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024163
 protein coding gene Chr17:43404382-43409044 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0022966
 protein coding gene Chr17:41451744-41456405 (+)
CBA/J MGP_CBAJ_G0023461
 protein coding gene Chr17:44935608-44940268 (+)
DBA/2J MGP_DBA2J_G0023587
 protein coding gene Chr17:39396981-39401443 (+)
FVB/NJ MGP_FVBNJ_G0023554
 protein coding gene Chr17:39034661-39039318 (+)
LP/J MGP_LPJ_G0023668
 protein coding gene Chr17:42170210-42180426 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023583
 protein coding gene Chr17:44361655-44366753 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024209
 protein coding gene Chr17:41079633-41084295 (+)
PWK/PhJ MGP_PWKPhJ_G0022711
 protein coding gene Chr17:38763677-38768441 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0023031
 protein coding gene Chr17:41631864-41637048 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 619517 NCBI Gene Model | MGI Sequence Detail 4663 C57BL/6J ±  kb
transcript NM_001038500 RefSeq | MGI Sequence Detail 1049 C57BL/6  
polypeptide Q3LHH8 UniProt | EBI | MGI Sequence Detail 102 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • PDB
    2LMK
  • InterPro Domains
    IPR043126 Esp1, core domain
    IPR032253 Exocrine gland-secreted peptide Esp1/Esp22
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 17
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:106002 Kimoto H, et al., Sex-specific peptides from exocrine glands stimulate mouse vomeronasal sensory neurons. Nature. 2005 Oct 6;437(7060):898-901
  • Latest
    J:329616 Hattori T, et al., Exocrine Gland-Secreting Peptide 1 Is a Key Chemosensory Signal Responsible for the Bruce Effect in Mice. Curr Biol. 2017 Oct 23;27(20):3197-3201.e3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory