Gng14 Gene Detail

Summary

• Symbol
  Gng14
• Name
  G protein subunit gamma 14
• Synonyms
  Gm5741

• Feature Type
  protein coding gene
• IDs
  MGI:3645690
  NCBI Gene: 100503710
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr8:85794197-85794611 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  103 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3645690	protein coding gene	Chr8:85794141-85794647 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0033891	protein coding gene	Chr8:86014220-86014634 (-)
A/J	MGP_AJ_G0033874	protein coding gene	Chr8:82615998-82616412 (-)
AKR/J	MGP_AKRJ_G0033800	protein coding gene	Chr8:85073087-85073501 (-)
BALB/cJ	MGP_BALBcJ_G0033867	protein coding gene	Chr8:82751451-82751865 (-)
C3H/HeJ	MGP_C3HHeJ_G0033577	protein coding gene	Chr8:85691752-85692166 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0034387	protein coding gene	Chr8:89305576-89305990 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031328	protein coding gene	Chr8:76419182-76419577 (-)
CAST/EiJ	MGP_CASTEiJ_G0032907	protein coding gene	Chr8:85122821-85123235 (-)
CBA/J	MGP_CBAJ_G0033553	protein coding gene	Chr8:92336355-92336769 (-)
DBA/2J	MGP_DBA2J_G0033706	protein coding gene	Chr8:82254587-82255001 (-)
FVB/NJ	MGP_FVBNJ_G0033654	protein coding gene	Chr8:81213839-81214253 (-)
LP/J	MGP_LPJ_G0033798	protein coding gene	Chr8:86119002-86119416 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0033696	protein coding gene	Chr8:94897857-94898271 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034404	protein coding gene	Chr8:85061744-85062158 (-)
PWK/PhJ	MGP_PWKPhJ_G0032610	protein coding gene	Chr8:81501645-81502059 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0032447	protein coding gene	Chr8:83881600-83882014 (-)
WSB/EiJ	MGP_WSBEiJ_G0033020	protein coding gene	Chr8:85489136-85489550 (-)

Homology

• Human Ortholog
  GNG14, G protein subunit gamma 14

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  GNG14, G protein subunit gamma 14
  
• Synonyms
  HG3K
• Links
  HGNC:53439

  NCBI Gene ID: 105372280

  UniProt: A0A1W2PPG7

  
  
• Chr Location
  chr19:12687998-12688422 (+)  GRCh38

---

• MGI Vertebrate Homology
  Gng14 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: GNG14
• Gene Tree
  Gng14
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  34 phenotype references
  

• All Mutations and Alleles
  7
• Chemically induced (other)
  1
• Gene trapped
  5
• Radiation induced
  1
• Genomic Mutations
  2 involving Gng14
• Find Mice (IMSR)
  2 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  2

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  28
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS57629.1

• Ensembl
  ENSMUSG00000095845 (Evidence)
• NCBI Gene
  100503710

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000095845	Ensembl Gene Model | MGI Sequence Detail	415	C57BL/6J
transcript	ENSMUST00000177563	Ensembl | MGI Sequence Detail	328	Not Applicable
polypeptide	ENSMUSP00000136655	Ensembl | MGI Sequence Detail	72	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR015898 G-protein gamma-like domain
  IPR036284 G-protein gamma-like domain superfamily
  IPR001770 G-protein, gamma subunit

Molecular
Reagents

• All nucleic 2

  cDNA 2

Other
Accession IDs

MGI:7284406

References

• Summaries
  All 41

  Phenotypes 34
• Earliest
  J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
• Latest
  J:348117 Okuma H, et al., N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on alpha-dystroglycan and prevents muscular dystrophy. Elife. 2023 Feb 1;12