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Defa42 Gene Detail
Summary
  • Symbol
    Defa42
  • Name
    defensin, alpha, 42
  • Synonyms
    Gm7849
  • Feature Type
    protein coding gene
  • IDs
    MGI:3645033
    NCBI Gene: 665927
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr8:21455427-21456517 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 10.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645033
protein coding gene Chr8:21455427-21456560 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033428
protein coding gene Chr8:19091473-19092599 (-)
A/J MGP_AJ_G0033409
protein coding gene Chr8:18884620-18887256 (-)
AKR/J MGP_AKRJ_G0033337
protein coding gene Chr8:19389499-19390527 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0033119
protein coding gene Chr8:19657321-19658978 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0030884
protein coding gene Chr8:15504494-15505538 (-)
CAST/EiJ MGP_CASTEiJ_G0032446
protein coding gene Chr8:19119751-19120865 (-)
CBA/J MGP_CBAJ_G0033095
protein coding gene Chr8:21135163-21137859 (-)
DBA/2J MGP_DBA2J_G0033249
protein coding gene Chr8:18861097-18862464 (-)
FVB/NJ MGP_FVBNJ_G0033194
protein coding gene Chr8:18512457-18518771 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0033237
protein coding gene Chr8:20782229-20783341 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033942
protein coding gene Chr8:19402812-19407586 (-)
PWK/PhJ MGP_PWKPhJ_G0032157
protein coding gene Chr8:18272696-18273810 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0032561
protein coding gene Chr8:19275053-19276164 (-)



Homology
less
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 665927 NCBI Gene Model | MGI Sequence Detail 1091 C57BL/6J ±  kb
transcript NM_001177518 RefSeq | MGI Sequence Detail 463 C57BL/6  
polypeptide NP_001170989 RefSeq | MGI Sequence Detail 116 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR016327 Alpha-defensin propeptide
    IPR002366 Defensin propeptide
References
more
  • Summaries
    All 8
    Gene Ontology 1
  • Earliest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory