Gml Gene Detail

Summary

• Symbol
  Gml
• Name
  glycosylphosphatidylinositol anchored molecule like
• Synonyms
  EG625599

• Feature Type
  protein coding gene
• IDs
  MGI:3644767
  NCBI Gene: 625599
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr15:74813452-74818815 bp, - strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 15, 34.28 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  15 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3644767	protein coding gene	Chr15:74813434-74820049 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0021940	protein coding gene	Chr15:74614443-74619217 (+)
A/J	MGP_AJ_G0021899	protein coding gene	Chr15:71941891-71947823 (-)
AKR/J	MGP_AKRJ_G0021881	protein coding gene	Chr15:73778744-73789015 (-)
BALB/cJ	MGP_BALBcJ_G0021906	protein coding gene	Chr15:71957176-71968692 (+)
C3H/HeJ	MGP_C3HHeJ_G0021679	protein coding gene	Chr15:73946670-73955197 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0022346	protein coding gene	Chr15:77424027-77429457 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019881	protein coding gene	Chr15:68351869-68355909 (+)
CAST/EiJ	MGP_CASTEiJ_G0021198	protein coding gene	Chr15:74774646-74782166 (-)
CBA/J	MGP_CBAJ_G0021645	protein coding gene	Chr15:79956890-79967853 (-)
DBA/2J	MGP_DBA2J_G0021770	protein coding gene	Chr15:71534757-71538881 (-)
FVB/NJ	MGP_FVBNJ_G0021752	protein coding gene	Chr15:70581295-70586637 (-)
LP/J	MGP_LPJ_G0021842	protein coding gene	Chr15:74673302-74695340 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021776	protein coding gene	Chr15:85262311-85266450 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022367	protein coding gene	Chr15:74173517-74184929 (-)
PWK/PhJ	MGP_PWKPhJ_G0020941	protein coding gene	Chr15:71673783-71676860 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0020782	protein coding gene	Chr15:74066075-74073378 (-)
WSB/EiJ	MGP_WSBEiJ_G0021250	protein coding gene	Chr15:74200643-74205854 (-)

Homology

• Human Ortholog
  GML, glycosylphosphatidylinositol anchored molecule like

• Vertebrate Orthologs
  8

• Human Ortholog
  GML, glycosylphosphatidylinositol anchored molecule like
  Orthology source: HomoloGene, HGNC
• Synonyms
  LY6DL
• Links
  HGNC:4375

  NCBI Gene ID: 2765

  neXtProt AC: NX_Q99445

  UniProt: Q99445

  
  
• Chr Location
  8q24.3; chr8:142834801-142846846 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 48071
  1 human;2 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 macaque, rhesus
  
• HCOP
  human homology predictions: GML
• Protein SuperFamily
  Ly-6-like protein
• Gene Tree
  Gml
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  22 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  3
• Radiation induced
  2
• Genomic Mutations
  5 involving Gml
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  8 strains or lines available

Expression

• cDNA Data
  2

• Other Mouse Links
  GEO
  Expression Atlas

Interactions

• Gml interacts with 25 markers (Mir18, Mir18b, Mir134, ...) View All

Sequences &
Gene Models

• All Sequences
  44
• RefSeq
  12
• UniProt
  3
• CCDS
  CCDS49637.1
• UniGene
  390785

• Ensembl
  ENSMUSG00000068349 (Evidence)
• NCBI Gene
  625599

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000068349	Ensembl Gene Model | MGI Sequence Detail	5364	C57BL/6J
transcript	ENSMUST00000096400	Ensembl | MGI Sequence Detail	957	Not Applicable
polypeptide	ENSMUSP00000094131	Ensembl | MGI Sequence Detail	176	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• InterPro Domains
  IPR016054 Ly-6 antigen/uPA receptor-like

Molecular
Reagents

• All nucleic 2

  cDNA 2

  
  

  Microarray probesets 1

References

• Summaries
  All 32

  Diseases 1

  Phenotypes 22
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

TSS for Gml:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr134756	Chr15:74818722-74818735 (-)	86 bp
Tssr134755	Chr15:74817288-74817297 (-)	1,522 bp