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Spink7 Gene Detail
Summary
  • Symbol
    Spink7
  • Name
    serine peptidase inhibitor, Kazal type 7 (putative)
  • Synonyms
    EG408198
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644691
    NCBI Gene: 408198
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:62592194-62596327 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 35.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    92 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644691
protein coding gene Chr18:62592194-62596568 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024492
protein coding gene Chr18:62535892-62539743 (-)
A/J MGP_AJ_G0024459
protein coding gene Chr18:59853894-59857738 (-)
AKR/J MGP_AKRJ_G0024429
protein coding gene Chr18:61512046-61515893 (-)
BALB/cJ MGP_BALBcJ_G0024458
protein coding gene Chr18:59987618-59991462 (-)
C3H/HeJ MGP_C3HHeJ_G0024226
protein coding gene Chr18:61749292-61753228 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024905
protein coding gene Chr18:64223667-64227518 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022336
protein coding gene Chr18:59384313-59388258 (-)
CAST/EiJ MGP_CASTEiJ_G0023699
protein coding gene Chr18:61618326-61622169 (-)
CBA/J MGP_CBAJ_G0024196
protein coding gene Chr18:66298766-66302610 (-)
DBA/2J MGP_DBA2J_G0024326
protein coding gene Chr18:59521750-59525601 (-)
FVB/NJ MGP_FVBNJ_G0024292
protein coding gene Chr18:58924843-58928694 (-)
LP/J MGP_LPJ_G0024410
protein coding gene Chr18:62416415-62420266 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024321
protein coding gene Chr18:67853048-67856899 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024952
protein coding gene Chr18:61708226-61712077 (-)
PWK/PhJ MGP_PWKPhJ_G0023442
protein coding gene Chr18:59757553-59761398 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023248
protein coding gene Chr18:61937777-61941618 (-)
WSB/EiJ MGP_WSBEiJ_G0023763
protein coding gene Chr18:61573829-61577680 (-)



Homology
more
  • Human Ortholog
    SPINK7, serine peptidase inhibitor Kazal type 7
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SPINK7, serine peptidase inhibitor Kazal type 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ECG2, ECRG2
  • Links
    NCBI Gene ID: 84651
    neXtProt AC: NX_P58062
    UniProt: P58062

  • Chr Location
    5q32; chr5:148312427-148315919 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060201 Ensembl Gene Model | MGI Sequence Detail 4134 C57BL/6J ±  kb
transcript ENSMUST00000076194 Ensembl | MGI Sequence Detail 540 Not Applicable  
polypeptide ENSMUSP00000075551 Ensembl | MGI Sequence Detail 85 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 12
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory